SynthesisInternational journal of environmental research and public health2021
Association between Body Composition and Bone Mineral Density in Children and Adolescents: A Systematic Review and Meta-Analysis.
Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Socioeconomic differences in bone mass in pediatric populations: A systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Pooled it
- Lean and fat mass associations with areal bone mineral density in adolescent team sport athletes.Journal of bone and mineral metabolism · 2026Article
- Correlations among whole-body fat, bone, and biomarkers in boys and girls with obesity: a cross-sectional study.Annals of pediatric endocrinology & metabolism · 2026Article
- Sex- and Age-Specific Associations Between Visceral Fat-to-Muscle Ratio and Bone Mineral Density in Children and Adolescents.International journal of endocrinology · 2026Article
- Article
- Exposure to high altitude is associated with an elevated risk of hip fracture: a retrospective cohort study using data from the CHARLS.BMC geriatrics · 2025Article
- Association between lean mass, fat mass, and waist circumference with bone mineral density in Mexican children and adolescents: a cross-sectional study.European journal of pediatrics · 2025Article
- Effects of Oral Nutritional Supplementation on Body Composition and Bone Health in Undernourished Children: A Randomized Controlled Study.Journal of clinical medicine · 2025Article
- Bone mineral density in childhood acute lymphoblastic leukaemia survivors and factors affecting it.Medical journal, Armed Forces India · 2025Article
- Comparison of adult height prediction using bone age and body composition for growth assessment in Korean children.Scientific reports · 2025Article
- Association Between the Bone Density of Alveolar and General Skeletal Bones in the Young.Cureus · 2025Article
- Correlation of body compositions and bone mineral density in postmenopausal women with different body mass index.Frontiers in endocrinology · 2025Article
- Age-dependent association between lifestyle oxidative balance score and bone mineral density in children and adolescents: evidence from the NHANES 2015-2018.Frontiers in physiology · 2025Article
- Insufficient Bone Mineralization to Sustain Mechanical Load of Weight in Obese Boys: A Cross-Sectional Study.The Journal of clinical endocrinology and metabolism · 2024Article
- Body composition in adults born preterm with very low birth weight.Pediatric research · 2024Article
- Maternal pre-pregnancy body mass index and related factors: A cross-sectional analysis from the Japan Environment and Children's Study.PloS one · 2024Article
- Determinants of bone mineral density in various regions of the skeleton among smokers and non-smokers: the role of physical activity.Frontiers in physiology · 2024Article
- Factors Associated With Weight Loss After Laparoscopic Adjustable Gastric Banding in Adolescents With Severe Obesity.JPGN reports · 2023Article
- High prevalence of low bone mineral density but normal trabecular bone score in Norwegian elite Para athletes.Frontiers in sports and active living · 2023Article
- The causal relationship between gut microbiota and bone mineral density: a Mendelian randomization study.Frontiers in microbiology · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBone mass acquisition during growth is a major determinant of the risk of developing osteoporosis later in life. Body composition is an anthropometric determinant of bone mineral density (BMD) and significantly influences its development during childhood and adolescence.
objectiveThis study aimed to systematically examine the association between body composition and bone mineral density in children and adolescents.
methodsObservational studies addressing this association were identified from PubMed (MEDLINE), Embase, Scopus and the Cochrane Library (up to January 2021). The study populations consisted of healthy children and adolescents. The DerSimonian and Laird method was used to compute pooled estimates of effect size and the respective 95% confidence intervals for upper limbs, femoral neck (FN), lumbar spine (LS) and total body, respectively. Subgroup analyses were further performed based on age, sex and ethnicity.
resultsThirty-one published studies were eligible for inclusion in this systematic review and meta-analysis, including three longitudinal studies. The combined population from all the studies amounted to 21,393 (11,205 males and 10,188 females). The pooled estimates of the correlation coefficients for lean mass (LM) and BMD ranged from 0.53 to 0.74 (
conclusionsThis systematic review and meta-analysis supports a positive association between LM and BMD. BF% appears to have a deleterious effect on bone acquisition in children and adolescents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.