Evidence map›Paper›PMID 34831809›Full record

ArticleInternational journal of environmental research and public health2021

Pediatric Hospitalization for Varicella in an Italian Pediatric Hospital: How Much Does It Cost?

Elena Bozzola, Giulia Spina, Maria Rosaria Marchili, Carla Brusco, Stefano Guolo, Chiara Rossetti, Giuseppe Logrieco, Francesca Pignatelli, Massimiliano Raponi, Alberto Villani

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Elena BozzolaPediatric Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, 00100 Roma, Italy.ORCID 0000-0001-5947-2414
Giulia SpinaPediatric Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, 00100 Roma, Italy.ORCID 0000-0002-5685-5468
Maria Rosaria MarchiliPediatric Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, 00100 Roma, Italy.
Carla BruscoSanitary Direction, Bambino Gesù Children's Hospital, IRCCS, 00100 Roma, Italy.
Stefano GuoloSanitary Direction, Bambino Gesù Children's Hospital, IRCCS, 00100 Roma, Italy.
Chiara RossettiPediatric Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, 00100 Roma, Italy.
Giuseppe LogriecoPediatric Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, 00100 Roma, Italy.
Francesca PignatelliPediatric Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, 00100 Roma, Italy.
Massimiliano RaponiSanitary Direction, Bambino Gesù Children's Hospital, IRCCS, 00100 Roma, Italy.
Alberto VillaniPediatric Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, 00100 Roma, Italy.ORCID 0000-0002-9120-0424
Bambino Gesù Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVaricella is a common pediatric infection. Even if it generally has a benign course, it may complicate and require hospitalization. The aim of our study was to estimate the acute hospitalization cost (AHC) for varicella in the acute phase in a pediatric population.

methodsWe calculated the AHC of pediatric patients admitted for varicella at Bambino Gesù Children Hospital, Rome, Italy, from 1 November 2005 to 1 November 2020.

resultsIn the study period, 825 pediatric patients affected by varicella were hospitalized. The mean hospitalization cost was EUR 4015.35 (range from EUR 558.44 to EUR 42,608.00). Among patients, 55% were unvaccinable due to either their age or their immunosuppression status. They would benefit from herd immunity, reducing the overall AHC by EUR 182,196,506. Since the introduction of the compulsory vaccination against varicella in Italy, we observed a significant reduction in AHC cost of 60.6% in 2019 and of 93.5% in 2020. Finally, from the beginning of the COVID-19 pandemic, we documented a decline of 81.2% and 76.9% in varicella hospitalization, compared to 2018 and 2019, respectively.

conclusionsVaricella AHC is an important economic and health assessment point and can be useful for improving preventive strategies.

Indexed as

ChickenpoxCOVID-19Chickenpox VaccineChildHospitalizationHospitals, PediatricHumansInfantItalyPandemicsSARS-CoV-2Chickenpox Vaccinechildrencosthospitalizationvaricella

Identifiers

PMID34831809
PMCPMC8617963
OpenAlexW3213776785

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.