Trial reportInternational journal of environmental research and public health2021
Night Shift and Decreased Brain Activity of ICU Nurses: A Near-Infrared Spectroscopy Study.
Trial report in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Working against the clock: the impact of shift patterns on cognitive function, mental health, and stimulant use among healthcare workers.BMC psychiatry · 2026Article
- Intensive care unit nurses' perceptions of night-work-related chronic fatigue and cognitive function: a cross-sectional survey.Frontiers in public health · 2026Article
- Effects of Night Shifts on Sleep, Cognitive Performance, and Anxiety in Emergency Nurses: An Observational Within-Subject Study.Journal of nursing management · 2026Observational
- Effects of single- and double-shift work on hand and cognitive functions in nurses.International nursing review · 2025Article
- Fatigue and coping strategies among Chinese night-shift nurses: a cross-sectional study.BMC nursing · 2025Article
- Work-related stress in intensive care unit night shift nurses: A cross-sectional analysis of prevalence and determinants.PloS one · 2025Article
- Long-term night-shift work is associated with accelerates brain aging and worsens N3 sleep in female nurses.Sleep medicine · 2024Article
- Alterations of functional brain activity and connectivity in female nurses working on long-term shift.Nursing open · 2024Article
- Article
- The impact of 24-hour sleep deprivation on cognition and inflammatory response in anesthesiologists and nurses in operating rooms.Saudi journal of anaesthesiaArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundShift working is associated with a profound desynchronization of circadian rhythm and in particular, night-shift work disrupts normal circadian physiology. Sleep deprivation affects the functioning of certain brain areas and thus impairs cognitive performance. The purpose of this study was to investigate the effects of the night shift on cognitive performance and cerebral oxygenation/haemodynamics.
methodsA prospective, observational, comparative, randomized and cross-over study was carried out. A total of 74 intensive care unit nurses in Spain were included in the study. The following variables were measured: sociodemographic, burnout, anxiety, baseline cerebral oxygenation levels on night and day shift using a near-infrared spectroscopy system and cognitive task performance during a verbal fluency task to evaluate the alterations in the prefrontal cortex, assessed as changes in regional saturation index.
resultsThe average regional saturation index decreased significantly in the night shift (r = 0.560,
conclusionsSleep deprivation during the night shift was considered to be related to decreased dorsolateral PFC reactivity. After the night shift, the nurses showed a decrease in prefrontal cortex activity and in cognitive performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.