Evidence map›Paper›PMID 34831657›Full record

ArticleInternational journal of environmental research and public health2021

Reduction in Blood Lead Concentration in Children across the Republic of Georgia following Interventions to Address Widespread Exceedance of Reference Value in 2019.

Ekaterine Ruadze, Giovanni S Leonardi, Ayoub Saei, Irma Khonelidze, Lela Sturua, Vladimer Getia, Helen Crabbe, Tim Marczylo, Paolo Lauriola, Amiran Gamkrelidze

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Identifying Sources of Lead Exposure for Children in the Republic of Georgia, with Lead Isotope Ratios.International journal of environmental research and public health · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Ekaterine RuadzeThe National Center for Disease Control and Public Health of Georgia, Tbilisi 0198, Georgia.
Giovanni S LeonardiUK Health Security Agency, Radiation, Chemical and Environmental Hazards, Harwell Campus, Didcot OX11 0RQ, UK.ORCID 0000-0001-7477-1762
Ayoub SaeiUK Health Security Agency, Statistics Unit, Department of Statistics, Modelling and Economics, London NW9 5EQ, UK.
Irma KhonelidzeThe National Center for Disease Control and Public Health of Georgia, Tbilisi 0198, Georgia.
Lela SturuaThe National Center for Disease Control and Public Health of Georgia, Tbilisi 0198, Georgia.ORCID 0000-0002-8242-1145
Vladimer GetiaThe National Center for Disease Control and Public Health of Georgia, Tbilisi 0198, Georgia.
Helen CrabbeUK Health Security Agency, Radiation, Chemical and Environmental Hazards, Harwell Campus, Didcot OX11 0RQ, UK.ORCID 0000-0002-8548-5785
Tim MarczyloUK Health Security Agency, Radiation, Chemical and Environmental Hazards, Harwell Campus, Didcot OX11 0RQ, UK.ORCID 0000-0001-9744-473X
Paolo LauriolaInternational Society of Doctors for the Environment-Italy (ISDE-Italy), 42122 Modena, Italy.ORCID 0000-0003-4768-6612
Amiran GamkrelidzeThe National Center for Disease Control and Public Health of Georgia, Tbilisi 0198, Georgia.
National Center for Disease Control and Public Health · GEUK Health Security Agency · GBUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, reports of lead contamination have dramatically increased in Georgia. Given concerns about the exposure of children to lead (Pb), the National Multiple Indicator Cluster Survey (MICS-2018) included a blood sampling component. The results showed that 41% of the children that participated had blood Pb levels (BLL) ≥ 5 µg/dL and that BLL in children living in Western Georgia were higher than those in Eastern regions. In response to these findings, NCDC implemented written and verbal advice to the families of children who participated in the MICS-2018 on how to reduce Pb exposure. From August 2019 onwards, the state program of clinical follow-up was implemented. The design of this study was a longitudinal study. The intervention of interest was the public health advice and medical follow-up, and the outcome was defined as the difference in BLL between the MICS-2018 survey and the state program follow-up. We observed a significant overall reduction in median BLL between MICS-2018 and state program follow-up in both August 2019 and the latest results (until December 2019). However, we did not observe any significant further reduction between August and the most recent BLL results. In the Georgian setting, written and verbal communication targeting individual households, alongside home visits to the most exposed, effectively reduced BLL in children.

Indexed as

LeadLead PoisoningChildEnvironmental ExposureGeorgiaGeorgia (Republic)HumansLongitudinal StudiesReference ValuesLeadGeorgialead (Pb)multiple stakeholder responsepublic health interventionsstate programwritten and verbal communication

Identifiers

PMID34831657
PMCPMC8621835
OpenAlexW3212196995

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.