Evidence map›Paper›PMID 34831562›Full record

SynthesisInternational journal of environmental research and public health2021

Virtual Reality in the Treatment of Adults with Chronic Low Back Pain: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Beatriz Brea-Gómez, Irene Torres-Sánchez, Araceli Ortiz-Rubio, Andrés Calvache-Mateo, Irene Cabrera-Martos, Laura López-López, Marie Carmen Valenza

5 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 54 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06248216 narecruitingnot on this mapstarted 2024, after this paper: background citation

Implementation of an At-Home Multimodal Integrative Therapy Via Virtual Reality for Patients With Cancer-Treatment Associated Symptoms

TypeinterventionalSponsorUniversity of Maryland, BaltimoreRan2024 to 2027Enrolled30ConditionsCancer, Cancer Pain, Virtual RealityArmsRelievrx, Audio Mp4
NCT07172828 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Investigation of the Effects of Virtual Reality-Based Rehabilitation on Muscle Architecture, Balance Control, and Patient Satisfaction in Individuals With Chronic Low Back Pain

TypeinterventionalSponsorHacettepe UniversityRan2025 to 2026Enrolled48ConditionsChronic Low Back Pain (CLBP), Musculoskeletal Pain, Postural Balance, Exercise TherapyArmsVirtual Reality-Based Rehabilitation, Conventional Motor Control Exercises
NCT07240090 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Relation of Craniovertebral Angle With Lumbar Proprioception and Trunk Muscles Strength in Patients With Cervical Radiculopathy

TypeobservationalSponsorBasma Ashraf Ali MohamedRan2025 to 2026Enrolled64ConditionsCervical Radiculopathy
NCT07492784 nacompletednot on this mapstarted 2024, after this paper: background citation

Investigation of the Effect of a Virtual Reality-Based Back School Program on Pain, Functionality, and Kinesiophobia

TypeinterventionalSponsorHacettepe UniversityRan2024 to 2026Enrolled39ConditionsChronic Back and Leg PainArmsBack school education integrated with a VR headset
NCT07777679 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Randomized Controlled Pilot Trial Evaluating Virtual Reality-Based Cognitive Behavioral Therapy (VR-CBT) as a Prehabilitation Intervention for Adult Spinal Deformity Surgery

TypeinterventionalSponsorUniversity of California, IrvineRan2026 to 2028Enrolled80ConditionsDegenerative Spine Disease, Spinal Stenosis LumbarArmsVirtual Reality-Based CBT Prehabilitation (VR-CBT), CBT Prehabilitation without Virtual Reality
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Trial
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  11. Is therapeutic exercise as a standalone intervention effective in reducing kinesiophobia in adults with nonspecific chronic low back pain? A systematic review and meta-analysis with meta-regression.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
  12. Article
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  19. 14. Discogenic Low Back Pain.Pain practice : the official journal of World Institute of Pain · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Beatriz Brea-GómezPhysical Therapy Department, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.
Irene Torres-SánchezPhysical Therapy Department, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.ORCID 0000-0002-5459-230X
Araceli Ortiz-RubioPhysical Therapy Department, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.ORCID 0000-0002-7353-835X
Andrés Calvache-MateoPhysical Therapy Department, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.
Irene Cabrera-MartosPhysical Therapy Department, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.
Laura López-LópezPhysical Therapy Department, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.
Marie Carmen ValenzaPhysical Therapy Department, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.ORCID 0000-0003-2368-1307

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virtual reality (VR) can present advantages in the treatment of chronic low back pain. The objective of this systematic review and meta-analysis was to analyze the effectiveness of VR in chronic low back pain. This review was designed according to PRISMA and registered in PROSPERO (CRD42020222129). Four databases (PubMed, Cinahl, Scopus, Web of Science) were searched up to August 2021. Inclusion criteria were defined following PICOS recommendations. Methodological quality was assessed with the Downs and Black scale and the risk of bias with the Cochrane Risk of Bias Assessment Tool. Fourteen studies were included in the systematic review and eleven in the meta-analysis. Significant differences were found in favor of VR compared to no VR in pain intensity postintervention (11 trials;

Indexed as

Low Back PainPersons with DisabilitiesVirtual RealityAdultHumansRandomized Controlled Trials as Topicchronic low back painhorse simulator ridingphysical therapyrehabilitationvideogamesvirtual reality

Identifiers

PMID34831562
PMCPMC8621053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.