Evidence map›Paper›PMID 34831531›Full record

SynthesisInternational journal of environmental research and public health2021

In Vivo Imaging-Based Techniques for Early Diagnosis of Oral Potentially Malignant Disorders-Systematic Review and Meta-Analysis.

Marta Mazur, Artnora Ndokaj, Divyambika Catakapatri Venugopal, Michela Roberto, Cristina Albu, Maciej Jedliński, Silverio Tomao, Iole Vozza, Grzegorz Trybek, Livia Ottolenghi and 1 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Evaluation of Oral Mucosal Lesions Using the IllumiScanInternational journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marta MazurDepartment of Oral and Maxillo-Facial Sciences, Sapienza University, 00161 Rome, Italy.ORCID 0000-0002-0525-681X
Artnora NdokajDepartment of Oral and Maxillo-Facial Sciences, Sapienza University, 00161 Rome, Italy.ORCID 0000-0002-1400-8607
Divyambika Catakapatri VenugopalDepartment of Oral Medicine and Radiology, Faculty of Dental Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai 600116, India.ORCID 0000-0002-1344-8678
Michela RobertoMedical Oncology Unit, Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza University, 00161 Rome, Italy.ORCID 0000-0001-5339-8348
Cristina AlbuDepartment of Oral and Maxillo-Facial Sciences, Sapienza University, 00161 Rome, Italy.ORCID 0000-0003-0369-2703
Maciej JedlińskiDepartment of Interdisciplinary Dentistry, Pomeranian Medical University in Szczecin, 70111 Szczecin, Poland.ORCID 0000-0003-3446-6119
Silverio TomaoMedical Oncology Unit, Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza University, 00161 Rome, Italy.
Iole VozzaDepartment of Oral and Maxillo-Facial Sciences, Sapienza University, 00161 Rome, Italy.ORCID 0000-0001-8545-9889
Grzegorz TrybekDepartment of Oral Surgery, Pomeranian Medical University in Szczecin, 70111 Szczecin, Poland.ORCID 0000-0002-3900-4901
Livia OttolenghiDepartment of Oral and Maxillo-Facial Sciences, Sapienza University, 00161 Rome, Italy.ORCID 0000-0001-7390-4316
Fabrizio GuerraDepartment of Oral and Maxillo-Facial Sciences, Sapienza University, 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOral potentially malignant disorders (OPMDs) are lesions that may undergo malignant transformation to oral cancer. The early diagnosis and surveillance of OPMDs reduce the morbidity and mortality of patients. Diagnostic techniques based on medical images analysis have been developed to diagnose clinical conditions. This systematic review and meta-analysis aimed to evaluate the efficacy of imaging-based techniques compared to the gold standard of histopathology to assess their ability to correctly identify the presence of OPMDs.

designLiterature searches of free text and MeSH terms were performed using MedLine (PubMed), Scopus, Google Scholar, and the Cochrane Library (from 2000 to 30 June 2020). The keywords used in the search strategy were: ("oral screening devices" or "autofluorescence" or "chemiluminescence" or "optical imaging" or "imaging technique") and ("oral dysplasia" or "oral malignant lesions" or "oral precancerosis").

resultsThe search strategy identified 1282 potential articles. After analyzing the results and applying the eligibility criteria, the remaining 43 papers were included in the qualitative synthesis, and 34 of these were included in the meta-analysis.

conclusionsNone of the analyzed techniques based on assessing oral images can replace the biopsy. Further studies are needed to explore the role of techniques-based imaging analysis to identify an early noninvasive screening method.

Indexed as

Mouth DiseasesMouth NeoplasmsPrecancerous ConditionsBiopsyEarly Detection of CancerHumansdiagnosisimaging-based techniquesOPMDpotentially malignant oral lesions

Identifiers

PMID34831531
PMCPMC8622517

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.