Evidence map›Paper›PMID 34831476›Full record

ArticleCells2021

Effects of 5',8'-Cyclo-2'-Deoxypurines on the Base Excision Repair of Clustered DNA Lesions in Nuclear Extracts of the XPC Cell Line.

Julia Kaźmierczak-Barańska, Karolina Boguszewska, Michał Szewczuk, Bolesław T Karwowski

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. A perspective on tumor radiation resistance following high-LET radiation treatment.Journal of cancer research and clinical oncology · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Julia Kaźmierczak-BarańskaDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, 90-151 Lodz, Poland.ORCID 0000-0001-8560-5727
Karolina BoguszewskaDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, 90-151 Lodz, Poland.ORCID 0000-0003-3772-8540
Michał SzewczukDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, 90-151 Lodz, Poland.ORCID 0000-0002-5680-6594
Bolesław T KarwowskiDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, 90-151 Lodz, Poland.ORCID 0000-0001-6922-7834
Medical University of Lodz · PL

Funding

National Science Center 2016/23/B/NZ7/03367
6 · The paper itself

Abstract

Clustered DNA lesions (CDL) containing 5',8-cyclo-2'-deoxypurines (cdPus) are an example of extensive abnormalities occurring in the DNA helix and may impede cellular repair processes. The changes in the efficiency of nuclear base excision repair (BER) were investigated using (a) two cell lines, one of the normal skin fibroblasts as a reference (BJ) and the second from

Indexed as

DNA DamageDNA RepairCell LineCell NucleusHumansPurinesSubstrate SpecificityXeroderma PigmentosumPurinesBERBJcdAclustered DNA lesionsDNA damageDNA repairXPC

Identifiers

PMID34831476
PMCPMC8618216
OpenAlexW3217200417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.