Evidence map›Paper›PMID 34831336›Full record

ArticleCells2021

RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer's Disease.

Sanjay Awasthi, Ashly Hindle, Neha A Sawant, Mathew George, Murali Vijayan, Sudhir Kshirsagar, Hallie Morton, Lloyd E Bunquin, Philip T Palade, J Josh Lawrence and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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  12. Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer's Disease?International journal of molecular sciences · 2022
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Sanjay AwasthiDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0002-5214-5717
Ashly HindleDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Neha A SawantDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Mathew GeorgeDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Murali VijayanDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0002-7426-3415
Sudhir KshirsagarDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Hallie MortonDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Lloyd E BunquinDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Philip T PaladeDepartment of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
J Josh LawrenceDepartment of Pharmacology and Neuroscience and Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Hafiz KhanDepartment of Public Health, Graduate School of Biomedical Sciences, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Chhanda BoseDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
P Hemachandra ReddyDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0002-9560-9948
Sharda P SinghDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0003-4361-4558
Texas Tech University · USUniversity of Arkansas for Medical Sciences · US

Funding

DoD W81XWH-18-1-0534 SA
6 · The paper itself

Abstract

The purpose of our study is to understand the role of the

Indexed as

Oxidative StressAlzheimer DiseaseAnimalsAntioxidantsBehavior, AnimalCyclic AMP Response Element-Binding ProteinDisease Models, AnimalGene Expression RegulationGTPase-Activating ProteinsMiceMitochondriaMitochondrial DynamicsModels, BiologicalOrganelle BiogenesisRNA, MessengerSignal TransductionAntioxidantsCyclic AMP Response Element-Binding ProteinGTPase-Activating ProteinsRalbp1 protein, mouseRNA, MessengerAlzheimer’s diseasemitochondriamitochondrial biogenesismitophagysynaptic proteins

Identifiers

PMID34831336
PMCPMC8620796
OpenAlexW3213969099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.