Evidence map›Paper›PMID 34831330›Full record

ArticleCells2021

Apparent Yield Stress of Sputum as a Relevant Biomarker in Cystic Fibrosis.

Rosy Ghanem, Philippe Roquefort, Sophie Ramel, Véronique Laurent, Tanguy Haute, Tony Le Gall, Thierry Aubry, Tristan Montier

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  4. FeFrontiers in physiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rosy GhanemUniv. Brest, INSERM, EFS, UMR 1078, GGB, F-29200 Brest, France.ORCID 0000-0002-3336-6629
Philippe RoquefortUniv. Brest, IRDL UMR CNRS 6027, UFR Sciences et Techniques, 6, Avenue Victor Le Gorgeu CS 93837, CEDEX 3, 29238 Brest, France.
Sophie RamelCentre de Ressources et de Compétences de la Mucoviscidose, Fondation Ildys, Presqu'île de Perharidy, 29680 Roscoff, France.
Véronique LaurentUniv. Brest, INSERM, EFS, UMR 1078, GGB, F-29200 Brest, France.
Tanguy HauteUniv. Brest, INSERM, EFS, UMR 1078, GGB, F-29200 Brest, France.ORCID 0000-0002-7256-1785
Tony Le GallUniv. Brest, INSERM, EFS, UMR 1078, GGB, F-29200 Brest, France.ORCID 0000-0001-5922-5683
Thierry AubryUniv. Brest, IRDL UMR CNRS 6027, UFR Sciences et Techniques, 6, Avenue Victor Le Gorgeu CS 93837, CEDEX 3, 29238 Brest, France.
Tristan MontierUniv. Brest, INSERM, EFS, UMR 1078, GGB, F-29200 Brest, France.ORCID 0000-0003-0452-6395
Inserm · FRCentre National de la Recherche Scientifique · FR

Funding

Agence Nationale de la Recherche ANR-17-CE18-0015-03Association Gaétan Saleün Not applicableBrest Métropole Not applicable
6 · The paper itself

Abstract

The mucus obstructing the airways of Cystic Fibrosis (CF) patients is a yield stress fluid. Linear and non-linear rheological analyses of CF sputa can provide relevant biophysical markers, which could be used for the management of this disease. Sputa were collected from CF patients either without any induction or following an aerosol treatment with the recombinant human DNAse (rhDNAse, Pulmozyme

Indexed as

RheologyAdultBiomarkersCystic FibrosisElastic ModulusFemaleHumansMaleMucusNonlinear DynamicsReproducibility of ResultsSpecimen HandlingSputumBiomarkersairway mucusbiomarkerCystic Fibrosisrheology

Identifiers

PMID34831330
PMCPMC8619720
OpenAlexW3214415928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.