Evidence map›Paper›PMID 34831172›Full record

ReviewCells2021

Insights into COVID-19 Vaccine Development Based on Immunogenic Structural Proteins of SARS-CoV-2, Host Immune Responses, and Herd Immunity.

Jitendra Kumar Chaudhary, Rohitash Yadav, Pankaj Kumar Chaudhary, Anurag Maurya, Nimita Kant, Osamah Al Rugaie, Hoineiting Rebecca Haokip, Deepika Yadav, Rakesh Roshan, Ramasare Prasad and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Immunology of SARS-CoV-2 infection and vaccination.Clinica chimica acta; international journal of clinical chemistry · 2023
    Review
  11. Review
  12. Article
  13. Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Jitendra Kumar ChaudharyDepartment of Zoology, Shivaji College, University of Delhi, New Delhi 110027, India.ORCID 0000-0001-8499-9656
Rohitash YadavDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), Rishikesh 249201, India.ORCID 0000-0003-0859-5603
Pankaj Kumar ChaudharyMolecular Biology & Proteomics Laboratory, Department of Biotechnology, Indian Institute of Technology (IIT), Roorkee 247667, India.
Anurag MauryaDepartment of Botany, Shivaji College, University of Delhi, New Delhi 110027, India.
Nimita KantDepartment of Zoology, Shivaji College, University of Delhi, New Delhi 110027, India.ORCID 0000-0002-9156-4893
Osamah Al RugaieDepartment of Basic Medical Sciences, Unaizah College of Medicine and Medical Sciences, Qassim Uniersity, Unaizah 51911, Saudi Arabia.ORCID 0000-0001-8148-0138
Hoineiting Rebecca HaokipMedical Allied ICU, All India Institute of Medical Sciences, Rishikesh 249201, India.
Deepika YadavDepartment of Zoology, Shivaji College, University of Delhi, New Delhi 110027, India.ORCID 0000-0002-5496-2251
Rakesh RoshanDepartment of Zoology, Shivaji College, University of Delhi, New Delhi 110027, India.
Ramasare PrasadMolecular Biology & Proteomics Laboratory, Department of Biotechnology, Indian Institute of Technology (IIT), Roorkee 247667, India.ORCID 0000-0001-7341-2346
Apurva ChatrathMolecular Biology & Proteomics Laboratory, Department of Biotechnology, Indian Institute of Technology (IIT), Roorkee 247667, India.
Dharmendra SinghMolecular Biology & Proteomics Laboratory, Department of Biotechnology, Indian Institute of Technology (IIT), Roorkee 247667, India.ORCID 0000-0002-8898-060X
Neeraj JainDepartment of Cancer Biology, CSIR-Central Drug Research Institute, Lucknow 226031, India.ORCID 0000-0002-3736-8621
Puneet DhamijaDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), Rishikesh 249201, India.ORCID 0000-0002-2890-4939
University of Delhi · INIndian Institute of Technology Roorkee · INAll India Institute of Medical Sciences Rishikesh · INCentral Drug Research Institute · INQassim University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first quarter of the 21st century has remarkably been characterized by a multitude of challenges confronting human society as a whole in terms of several outbreaks of infectious viral diseases, such as the 2003 severe acute respiratory syndrome (SARS), China; the 2009 influenza H1N1, Mexico; the 2012 Middle East respiratory syndrome (MERS), Saudi Arabia; and the ongoing coronavirus disease 19 (COVID-19), China. COVID-19, caused by SARS-CoV-2, reportedly broke out in December 2019, Wuhan, the capital of China's Hubei province, and continues unabated, leading to considerable devastation and death worldwide. The most common target organ of SARS-CoV-2 is the lungs, especially the bronchial and alveolar epithelial cells, culminating in acute respiratory distress syndrome (ARDS) in severe patients. Nevertheless, other tissues and organs are also known to be critically affected following infection, thereby complicating the overall aetiology and prognosis. Excluding H1N1, the SARS-CoV (also referred as SARS-CoV-1), MERS, and SARS-CoV-2 are collectively referred to as coronaviruses, and taxonomically placed under the realm

Indexed as

Immunity, HerdAdaptive ImmunityCOVID-19COVID-19 VaccinesHumansImmunity, InnateSARS-CoV-2VaccinationVaccine DevelopmentViral Structural ProteinsCOVID-19 VaccinesViral Structural Proteinscoronavirus disease 19herd immunityimmune responseinfectious diseasepandemicSARS-CoV-2vaccination

Identifiers

PMID34831172
PMCPMC8616290
OpenAlexW3209345071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.