Evidence map›Paper›PMID 34831026›Full record

ArticleCells2021

Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL.

Manuel Olazábal-Morán, Miriam Sánchez-Ortega, Laura Martínez-Muñoz, Carmen Hernández, Manuel S Rodríguez, Mario Mellado, Ana C Carrera

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Manuel Olazábal-MoránDepartment of Immunology and Oncology, Centro Nacional de Biotecnología, CSIC-Campus Cantoblanco Autónoma University, 28049 Madrid, Spain.
Miriam Sánchez-OrtegaDepartment of Immunology and Oncology, Centro Nacional de Biotecnología, CSIC-Campus Cantoblanco Autónoma University, 28049 Madrid, Spain.
Laura Martínez-MuñozDepartment of Immunology and Oncology, Centro Nacional de Biotecnología, CSIC-Campus Cantoblanco Autónoma University, 28049 Madrid, Spain.ORCID 0000-0003-3098-279X
Carmen HernándezDepartment of Immunology and Oncology, Centro Nacional de Biotecnología, CSIC-Campus Cantoblanco Autónoma University, 28049 Madrid, Spain.
Manuel S RodríguezInstitut des Technologies Avancées en Sciences du Vivant (ITAV), 1 Place Pierre Potier, Université de Toulouse, CNRS, UPS, 31000 Toulouse, France.ORCID 0000-0001-5445-4495
Mario MelladoDepartment of Immunology and Oncology, Centro Nacional de Biotecnología, CSIC-Campus Cantoblanco Autónoma University, 28049 Madrid, Spain.ORCID 0000-0001-6325-1630
Ana C CarreraDepartment of Immunology and Oncology, Centro Nacional de Biotecnología, CSIC-Campus Cantoblanco Autónoma University, 28049 Madrid, Spain.ORCID 0000-0002-3999-5434
Centro Nacional de Biotecnología · ESCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

3-Poly-phosphoinositides (PIP

Indexed as

AnimalsCell CycleCell Line, TumorCell MembraneEpidermal Growth FactorErbB ReceptorsHEK293 CellsHumansMiceNIH 3T3 CellsPhosphatidylinositol PhosphatesPhosphorylationPlatelet-Derived Growth FactorProto-Oncogene Proteins c-aktProto-Oncogene Proteins c-cblPTEN PhosphohydrolaseEpidermal Growth FactorErbB Receptorsphosphatidylinositol 3,4,5-triphosphatePhosphatidylinositol PhosphatesPlatelet-Derived Growth FactorProto-Oncogene Proteins c-aktProto-Oncogene Proteins c-cblPTEN PhosphohydrolaseAKTCBLE3 ubiquitin ligasephosphatidylinositide 3-kinasePTEN

Identifiers

PMID34831026
PMCPMC8616390
OpenAlexW3206021083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.