Evidence map›Paper›PMID 34830942›Full record

ArticleCancers2021

High Grade of Amplification of Six Regions on Chromosome 2p in a Neuroblastoma Patient with Very Poor Outcome: The Putative New Oncogene

Marzia Ognibene, Loredana Amoroso, Fraia Melchionda, Davide Cangelosi, Federico Zara, Stefano Parodi, Annalisa Pezzolo

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marzia OgnibeneU.O.C. Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0003-3698-9319
Loredana AmorosoU.O.C. Oncologia Pediatrica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0003-1950-4754
Fraia MelchiondaU.O. Pediatria, Oncologia e Ematologia Pediatrica, IRCCS Azienda Ospedaliero-Universitaria S. Orsola, 40138 Bologna, Italy.
Davide CangelosiUnità di Bioinformatica Clinica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0002-6010-5619
Federico ZaraU.O.C. Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0001-9744-5222
Stefano ParodiUOSID Epidemiologia e Biostatistica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0002-9193-1622
Annalisa PezzoloIRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0001-6321-5701
Istituto Giannina Gaslini · IT

Funding

Compagnia San Paolo ID ROL 20207Ministero della Salute MSALRC21
6 · The paper itself

Abstract

We observed a case of high-risk neuroblastoma (NB) carried by a 28-month-old girl, displaying metastatic disease and a rapid decline of clinical conditions. By array-CGH analysis of the tumor tissue and of the metastatic bone marrow aspirate cells, we found a high-grade amplification of six regions besides

Indexed as

gene expressiongenomic amplificationneuroblastomasurvivalTSSC1

Identifiers

PMID34830942
PMCPMC8616235
OpenAlexW3214719524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.