Evidence map›Paper›PMID 34830843›Full record

ArticleCancers2021

Prostate-Specific Membrane Antigen in Anaplastic and Poorly Differentiated Thyroid Cancer-A New Diagnostic and Therapeutic Target?

Sabine Wächter, Pietro Di Fazio, Elisabeth Maurer, Jerena Manoharan, Corinna Keber, Andreas Pfestroff, Damiano Librizzi, Detlef K Bartsch, Markus Luster, Friederike Eilsberger

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Application of theranostics in thyroid cancer management.The Journal of clinical endocrinology and metabolism · 2026
    Review
  3. Review
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  7. Potential application of [EJNMMI research · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. [European journal of nuclear medicine and molecular imaging · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sabine WächterDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Marburg, 35043 Marburg, Germany.ORCID 0000-0003-3241-0728
Pietro Di FazioDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Marburg, 35043 Marburg, Germany.
Elisabeth MaurerDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Marburg, 35043 Marburg, Germany.
Jerena ManoharanDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Marburg, 35043 Marburg, Germany.ORCID 0000-0003-1611-2712
Corinna KeberDepartment of Pathology, University Hospital Marburg, 35043 Marburg, Germany.
Andreas PfestroffDepartment of Nuclear Medicine, University Hospital Marburg, 35043 Marburg, Germany.
Damiano LibrizziDepartment of Nuclear Medicine, University Hospital Marburg, 35043 Marburg, Germany.
Detlef K BartschDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Marburg, 35043 Marburg, Germany.
Markus LusterDepartment of Nuclear Medicine, University Hospital Marburg, 35043 Marburg, Germany.
Friederike EilsbergerDepartment of Nuclear Medicine, University Hospital Marburg, 35043 Marburg, Germany.
Philipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have demonstrated an expression of the prostate-specific membrane antigen (PSMA) in the cancer-related neovasculature of thyroid malignancies. Due to the poor prognosis and limited therapeutic options for patients with anaplastic (ATC) and poorly differentiated (PDTC) thyroid carcinoma, the aim of our study was to investigate the theranostic approach of PSMA expression in these patients. The PSMA uptake on Gallium-68 (

Indexed as

anaplastic thyroid carcinomaimmunohistochemistryneovasculaturepoorly differentiated thyroid carcinomaprostate-specific membrane antigentheranostictreatment

Identifiers

PMID34830843
PMCPMC8616254
OpenAlexW3211407962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.