Evidence map›Paper›PMID 34830819›Full record

ReviewCancers2021

Tetraspanins: Physiology, Colorectal Cancer Development, and Nanomediated Applications.

Stefan Titu, Cristiana Maria Grapa, Teodora Mocan, Ovidiu Balacescu, Alexandru Irimie

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Advances in endoscopic diagnosis and management of colorectal cancer.World journal of gastrointestinal oncology · 2024
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stefan Titu"Iuliu Hatieganu" University of Medicine and Pharmacy, Faculty of Medicine, 400126 Cluj-Napoca, Romania.
Cristiana Maria Grapa"Iuliu Hatieganu" University of Medicine and Pharmacy, Faculty of Medicine, 400126 Cluj-Napoca, Romania.
Teodora Mocan"Iuliu Hatieganu" University of Medicine and Pharmacy, Faculty of Medicine, 400126 Cluj-Napoca, Romania.
Ovidiu BalacescuDepartment of Genetics, Genomics and Experimental Pathology, The Oncology Institute "Prof. Dr. Ion Chiricuta" Cluj-Napoca, 400015 Cluj-Napoca, Romania.ORCID 0000-0003-0253-7103
Alexandru Irimie"Iuliu Hatieganu" University of Medicine and Pharmacy, Faculty of Medicine, 400126 Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · ROInstitute of Oncology Prof. Dr. Ion Chiricuta · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetraspanins are transmembrane proteins expressed in a multitude of cells throughout the organism. They contribute to many processes that surround cell-cell interactions and are associated with the progress of some diseases, including cancer. Their crucial role in cell physiology is often understated. Furthermore, recent studies have shown their great potential in being used as targeting molecules. Data have suggested the potential of tetraspanins as a targeting vector for nanomediated distribution and delivery for colorectal cancer applications. Our aim is to provide a review on the important part that tetraspanins play in the human organism and highlight their potential use for drug delivery systems using nanotechnology.

Indexed as

colorectal cancernanotechnologyphysiologytetraspanins

Identifiers

PMID34830819
PMCPMC8616055
OpenAlexW3212495280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.