Evidence map›Paper›PMID 34830805›Full record

ReviewCancers2021

Regulation of Adaptive Tumor Immunity by Non-Coding RNAs.

Eleftheria Papaioannou, María Del Pilar González-Molina, Ana M Prieto-Muñoz, Laura Gámez-Reche, Alicia González-Martín

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eleftheria PapaioannouDepartment of Biochemistry, Universidad Autónoma de Madrid (UAM), Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), 28029 Madrid, Spain.ORCID 0000-0003-1770-6600
María Del Pilar González-MolinaDepartment of Biochemistry, Universidad Autónoma de Madrid (UAM), Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), 28029 Madrid, Spain.ORCID 0000-0002-9509-0840
Ana M Prieto-MuñozDepartment of Biochemistry, Universidad Autónoma de Madrid (UAM), Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), 28029 Madrid, Spain.ORCID 0000-0001-7324-9219
Laura Gámez-RecheDepartment of Biochemistry, Universidad Autónoma de Madrid (UAM), Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), 28029 Madrid, Spain.ORCID 0000-0003-1649-0828
Alicia González-MartínDepartment of Biochemistry, Universidad Autónoma de Madrid (UAM), Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), 28029 Madrid, Spain.ORCID 0000-0002-6179-089X
Instituto de Investigaciones Biomédicas Sols-Morreale · ES

Funding

Community of Madrid, Spain SI1-PJI-2019-00241MCIN/AEI/10.13039/501100011033 FJC2019-040779-IMCIN/AEI/10.13039/ 501100011033 and FSE "El FSE invierte en tu futuro" PRE2019-087940MCIN/AEI/10.13039/501100011033/FEDER "Una manera de hacer Europa" RTI2018-100008-A-I00MCIN/AEI/10.13039/501100011033 y FSE "El FSE invierte en tu futuro" RyC-21155Spanish Association Against Cancer LAB-AECC 2020
6 · The paper itself

Abstract

Cancer immunology research has mainly focused on the role of protein-coding genes in regulating immune responses to tumors. However, despite more than 70% of the human genome is transcribed, less than 2% encodes proteins. Many non-coding RNAs (ncRNAs), including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), have been identified as critical regulators of immune cell development and function, suggesting that they might play important roles in orchestrating immune responses against tumors. In this review, we summarize the scientific advances on the role of ncRNAs in regulating adaptive tumor immunity, and discuss their potential therapeutic value in the context of cancer immunotherapy.

Indexed as

cancer immunotherapylong non-coding RNAsmicroRNAsnon-coding RNAstumor immunology

Identifiers

PMID34830805
PMCPMC8616131
OpenAlexW3212746089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.