Evidence map›Paper›PMID 34830766›Full record

ArticleCancers2021

Newly Diagnosed IDH-Wildtype Glioblastoma and Temporal Muscle Thickness: A Multicenter Analysis.

Tim Wende, Johannes Kasper, Gordian Prasse, Änne Glass, Thomas Kriesen, Thomas M Freiman, Jürgen Meixensberger, Christian Henker

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tim WendeDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.ORCID 0000-0002-8634-8897
Johannes KasperDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.ORCID 0000-0003-2122-2676
Gordian PrasseDepartment of Neuroradiology, University Hospital Leipzig, 04103 Leipzig, Germany.
Änne GlassInstitute of Biostatistics and Informatics in Medicine, University Medicine Rostock, 18057 Rostock, Germany.
Thomas KriesenDepartment of Neurosurgery, University Medical Center Rostock, 18057 Rostock, Germany.
Thomas M FreimanDepartment of Neurosurgery, University Medical Center Rostock, 18057 Rostock, Germany.
Jürgen MeixensbergerDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.
Christian HenkerDepartment of Neurosurgery, University Medical Center Rostock, 18057 Rostock, Germany.ORCID 0000-0002-7591-3192

Funding

University Leipzig Open Access Publishing
6 · The paper itself

Abstract

backgroundReduced temporal muscle thickness (TMT) has been discussed as a prognostic marker in IDH-wildtype glioblastoma. This retrospective multicenter study was designed to investigate whether TMT is an independent prognostic marker in newly diagnosed glioblastoma.

methodsTMT was retrospectively measured in 335 patients with newly diagnosed glioblastoma between 1 January 2014 and 31 December 2019 at the University Hospitals of Leipzig and Rostock. The cohort was dichotomized by TMT and tested for association with overall survival (OS) after 12 months by multivariate proportional hazard calculation.

resultsTMT of 7.0 mm or more was associated with increased OS (46.3 ± 3.9% versus 36.6 ± 3.9%,

conclusionTMT has not appeared as a statistically independent prognostic marker in this cohort of patients with newly diagnosed IDH-wildtype glioblastoma.

Indexed as

glioblastomaprognostic markersurvivaltemporal muscle thickness

Identifiers

PMID34830766
PMCPMC8615813

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.