Evidence map›Paper›PMID 34830728›Full record

ArticleJournal of clinical medicine2021

Feasibility and Clinical Outcomes of a Step Up Noninvasive Respiratory Support Strategy in Patients with Severe COVID-19 Pneumonia.

Silvia Coppola, Pierachille Santus, Giovanni Sotgiu, Michele Mondoni, Alessia Gandola, Marina Saad, Giuseppe Francesco Sferrazza Papa, Stefano Centanni, Laura Saderi, Davide Alberto Chiumello and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Silvia CoppolaDepartment of Anesthesia and Intensive Care, San Paolo Hospital, ASST Santi Paolo e Carlo, Via di Rudini 8, 20142 Milano, Italy.ORCID 0000-0001-9290-5090
Pierachille SantusDepartment of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Via G.B. Grassi 74, 20157 Milano, Italy.ORCID 0000-0003-3462-8253
Giovanni SotgiuDipartimento di Scienze Mediche, Chirurgiche e Sperimentali, Università degli Studi di Sassari, Viale San Pietro, 07100 Sassari, Italy.ORCID 0000-0002-1600-4474
Michele MondoniRespiratory Unit, San Paolo Hospital, ASST Santi Paolo e Carlo, Via di Rudinì 8, 20142 Milano, Italy.ORCID 0000-0001-9672-3534
Alessia GandolaDepartment of Anesthesia and Intensive Care, San Paolo Hospital, ASST Santi Paolo e Carlo, Via di Rudini 8, 20142 Milano, Italy.
Marina SaadDepartment of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Via G.B. Grassi 74, 20157 Milano, Italy.
Giuseppe Francesco Sferrazza PapaDepartment of Health Sciences, Università degli Studi di Milano, Via di Rudinì 8, 20142 Milano, Italy.
Stefano CentanniRespiratory Unit, San Paolo Hospital, ASST Santi Paolo e Carlo, Via di Rudinì 8, 20142 Milano, Italy.
Laura SaderiDipartimento di Scienze Mediche, Chirurgiche e Sperimentali, Università degli Studi di Sassari, Viale San Pietro, 07100 Sassari, Italy.ORCID 0000-0002-5131-9367
Davide Alberto ChiumelloDepartment of Anesthesia and Intensive Care, San Paolo Hospital, ASST Santi Paolo e Carlo, Via di Rudini 8, 20142 Milano, Italy.
Dejan RadovanovicDivision of Respiratory Diseases, L. Sacco University Hospital, ASST Fatebenefratelli-Sacco, Via G.B. Grassi 74, 20157 Milano, Italy.ORCID 0000-0002-9013-3418
University of Milan · ITOspedale San Paolo · ITUniversity of Sassari · ITASST Fatebenefratelli Sacco · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The best noninvasive respiratory strategy in patients with Coronavirus Disease 2019 (COVID-19) pneumonia is still discussed. We aimed at assessing the rate of endotracheal intubation (ETI) in patients treated with continuous positive airway pressure (CPAP) and noninvasive ventilation (NIV) if CPAP failed. Secondary outcomes were in-hospital mortality and in-hospital length of stay (LOS). A retrospective, observational, multicenter study was conducted in intermediate-high dependency respiratory units of two Italian university hospitals. Consecutive patients with COVID-19 treated with CPAP were enrolled. Thoraco-abdominal asynchrony or hemodynamic instability led to ETI. Patients showing SpO

Indexed as

acute respiratory failurecontinuous positive airway pressureCOVID-19intubationmortalitynoninvasive ventilation

Identifiers

PMID34830728
PMCPMC8620799
OpenAlexW3217663969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.