Evidence map›Paper›PMID 34830628›Full record

ArticleJournal of clinical medicine2021

AIDS Related Kaposi's Sarcoma: A 20-Year Experience in a Clinic from the South-East of Romania.

Manuela Arbune, Monica-Daniela Padurariu-Covit, Laura-Florentina Rebegea, Gabriela Lupasteanu, Anca-Adriana Arbune, Victorita Stefanescu, Alin-Laurentiu Tatu

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Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Manuela ArbuneClinical Medical Department, Medicine and Pharmacy Faculty, Dunarea de Jos University of Galati, 800008 Galati, Romania.
Monica-Daniela Padurariu-CovitClinical Medical Department, Medicine and Pharmacy Faculty, Dunarea de Jos University of Galati, 800008 Galati, Romania.ORCID 0000-0002-4237-2297
Laura-Florentina RebegeaClinical Medical Department, Medicine and Pharmacy Faculty, Dunarea de Jos University of Galati, 800008 Galati, Romania.
Gabriela LupasteanuInfectious Diseases I Department, Infectious Diseases Clinic Hospital Sf. Cuv. Parascheva, 800179 Galati, Romania.
Anca-Adriana ArbuneNeurology Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.ORCID 0000-0002-9500-4498
Victorita StefanescuMorphological and Functional Sciences Department, Dunarea de Jos University of Galati, 800008 Galati, Romania.
Alin-Laurentiu TatuClinical Medical Department, Medicine and Pharmacy Faculty, Dunarea de Jos University of Galati, 800008 Galati, Romania.
Clinical Emergency Hospital Bucharest · RO"Dunarea de Jos" University of Galati · ROInstitutul Clinic Fundeni · ROOvidius University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kaposi's sarcoma (KS) was peculiarly described in the first notified cases of the acquired immunodeficiency syndrome as an opportunistic condition. However, the medical progress and the development of active antiretroviral therapy allowed the control of the HIV/AIDS epidemic, although the features of KS have changed throughout the past decades. The purpose of our study is to assess the epidemiological and clinical features of AIDS related KS in Romanian patients. A retrospective follow-up study was achieved in a single infectious diseases' clinic from Galati-Romania, between 2001 and 2021. Referring to 290 new HIV diagnosed cases from our clinic retained in care, the prevalence of KS was 3.4%. The main characteristics of patients with KS are a median age of 33, a predominance of males, prevalent severe systemic forms of diseases, frequent association of past or concomitant tuberculosis, and context of immune reconstruction syndrome. The mortality rate was 70%. KS has occurred in patients with delayed HIV diagnoses and inadequate adherence to therapy. Early recognition of both infections, the close monitoring of latent or symptomatic tuberculosis, improving the antiretroviral adherence and raising the access to oncologic procedures in Romanian HIV patients could improve their prognosis related to KS.

Indexed as

AIDSco-infectionshighly active antiretroviral therapyimmune reconstruction inflammatory syndromeKaposi’s sarcoma

Identifiers

PMID34830628
PMCPMC8620409
OpenAlexW3214705063

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.