Evidence map›Paper›PMID 34830615›Full record

ArticleJournal of clinical medicine2021

Health-Related Quality of Life Issues Experienced by Thoracic and Breast Sarcoma Patients: A Rare and Understudied Group.

Ilse van Eck, Dide den Hollander, Emma Lidington, Leopold Hentschel, Martin Eichler, Samer Salah, Susanne Singer, Monica Pinto, Lena Fauske, Marco Fiore and 11 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 14 institutions in 8 countries.

Ilse van EckDepartment of Medical Oncology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands.
Dide den HollanderDepartment of Medical Oncology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0003-2077-2633
Emma LidingtonThe Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.ORCID 0000-0001-6176-8054
Leopold HentschelNational Center for Tumor Diseases (NCT/UCC), University Hospital Carl Gustav Carus, Technical University Dresden, 01307 Dresden, Germany.
Martin EichlerNational Center for Tumor Diseases (NCT/UCC), University Hospital Carl Gustav Carus, Technical University Dresden, 01307 Dresden, Germany.ORCID 0000-0001-9654-2207
Samer SalahDepartment of Medical Oncology, King Hussein Cancer Center, Amman 11941, Jordan.
Susanne SingerInstitute of Medical Biostatistics, Epidemiology and Informatics, University Medical Centre Mainz, 55131 Mainz, Germany.ORCID 0000-0001-5784-7964
Monica PintoRehabilitation Unit, Department of Supportive Care, Instituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131 Naples, Italy.
Lena FauskeDepartment of Oncology, The Norwegian Radium Hospital, Oslo University Hospital, 0379 Oslo, Norway.
Marco FioreDepartment of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.ORCID 0000-0001-8220-424X
Ioanna NixonDepartment of Clinical Oncology, Beatson West of Scotland Cancer Centre, Glasgow G12 0YN, UK.
Anastasia ConstantinidouMedical School University of Cyprus, Bank of Cyprus Oncology Centre, 1678 Nicosia, Cyprus.ORCID 0000-0001-5316-7574
Ingrid M E DesarDepartment of Medical Oncology, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Johannes J BonenkampDepartment of Surgical Oncology, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Winan J van HoudtDepartment of Surgical Oncology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-2303-3468
Milou J P ReuversDepartment of Medical Oncology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands.
Rick L M HaasDepartment of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0003-4834-4331
Øyvind S BrulandDepartment of Oncology, The Norwegian Radium Hospital, Oslo University Hospital, 0379 Oslo, Norway.
Bernd KasperSarcoma Unit, Mannheim University Medical Center, University of Heidelberg, 68167 Mannheim, Germany.ORCID 0000-0001-8425-8356
Winette T A van der GraafDepartment of Medical Oncology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0001-7549-3338
Olga HussonDepartment of Medical Oncology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-1387-8686
The Netherlands Cancer Institute · NLRadboud University Nijmegen · NLNational Center for Tumor Diseases · DEOslo University Hospital · NOBeatson West of Scotland Cancer Centre · GBErasmus MC · NLFondazione IRCCS Istituto Nazionale dei Tumori · ITHeidelberg University · DEInstitute of Cancer Research · GBIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITJohannes Gutenberg University Mainz · DEKing Hussein Cancer Center · JORoyal Marsden NHS Foundation Trust · GBUniversity of Cyprus · CY

Funding

EORTC Quality of Life Group 003-2018
6 · The paper itself

Abstract

Thoracic and breast sarcomas constitute a rare subgroup within the sarcoma population. There is limited knowledge about their health-related quality of life (HRQoL) and a valid disease-specific HRQoL instrument is lacking. This qualitative study aimed to investigate the HRQoL issues experienced by a small group of thoracic and breast sarcoma patients. Semi-structured interviews with 19 thoracic and four breast sarcoma patients were conducted and thematically analysed. Physical issues mentioned by both groups were fatigue, sleep disturbances, pain, wound infections, and symptoms related to chemotherapy and radiotherapy. Tightness in the back and restrictions in performing tasks above arm height were specific physical issues for breast sarcoma patients, whereas respiratory problems were only mentioned by thoracic sarcoma patients. Body image issues, changes in mood, fear of recurrence, and living with uncertainty were important mental health issues for both subgroups. Social issues in both groups included challenges in work and relationships, financial difficulties, loss of independence, and limitations in social activities. The identified physical, mental, and social health challenges can significantly impact thoracic and breast sarcoma patients' HRQoL. Results of this qualitative study will guide personalised supportive care for breast and thoracic sarcoma patients and help in determining the best possible HRQoL measurement strategy for sarcoma patients with different primary sarcoma locations.

Indexed as

breast sarcomachest sarcomahealth-related quality of lifepatient-reported outcomesthoracic sarcoma

Identifiers

PMID34830615
PMCPMC8618823
OpenAlexW3212329802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.