Evidence map›Paper›PMID 34830599›Full record

ArticleJournal of clinical medicine2021

Diabetes Mellitus in Prader-Willi Syndrome: Natural History during the Transition from Childhood to Adulthood in a Cohort of 39 Patients.

Alice Clerc, Muriel Coupaye, Héléna Mosbah, Graziella Pinto, Virginie Laurier, Fabien Mourre, Christine Merrien, Gwenaëlle Diene, Christine Poitou, Maithé Tauber

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Imprinting disorders.Nature reviews. Disease primers · 2023
    Review
  8. CD16Frontiers in immunology · 2023
    Article
  9. Article
  10. Approach to the Patient With Prader-Willi Syndrome.The Journal of clinical endocrinology and metabolism · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Alice ClercCentre de Référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et Autres Formes Rares d'Obésité avec Troubles du Comportement Alimentaire), Service d'Endocrinologie, Obésités, Maladies Osseuses, Génétique et Gynécologie Médicale, Hôpital des Enfants, 31059 Toulouse, France.
Muriel CoupayeAssistance Publique-Hôpitaux de Paris, Centre de Référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et Autres Formes Rares d'Obésité avec Troubles du Comportement Alimentaire), Service de Nutrition, Hôpital Pitié-Salpêtrière, 75013 Paris, France.ORCID 0000-0002-8988-6260
Héléna MosbahAssistance Publique-Hôpitaux de Paris, Centre de Référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et Autres Formes Rares d'Obésité avec Troubles du Comportement Alimentaire), Service de Nutrition, Hôpital Pitié-Salpêtrière, 75013 Paris, France.ORCID 0000-0001-7360-4209
Graziella PintoAssistance Publique-Hôpitaux de Paris, Service d'Endocrinologie, Gynécologie et Diabétologie Pédiatrique, Hôpital Necker-Enfants Malades, 75743 Paris, France.
Virginie LaurierAssistance Publique-Hôpitaux de Paris, Centre de Référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et Autres Formes Rares d'Obésité avec Troubles du Comportement Alimentaire), Hôpital Marin d'Hendaye, 64701 Hendaye, France.
Fabien MourreAssistance Publique-Hôpitaux de Paris, Centre de Référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et Autres Formes Rares d'Obésité avec Troubles du Comportement Alimentaire), Hôpital Marin d'Hendaye, 64701 Hendaye, France.
Christine MerrienAssistance Publique-Hôpitaux de Paris, Centre de Référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et Autres Formes Rares d'Obésité avec Troubles du Comportement Alimentaire), Hôpital Marin d'Hendaye, 64701 Hendaye, France.
Gwenaëlle DieneCentre de Référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et Autres Formes Rares d'Obésité avec Troubles du Comportement Alimentaire), Service d'Endocrinologie, Obésités, Maladies Osseuses, Génétique et Gynécologie Médicale, Hôpital des Enfants, 31059 Toulouse, France.
Christine PoitouAssistance Publique-Hôpitaux de Paris, Centre de Référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et Autres Formes Rares d'Obésité avec Troubles du Comportement Alimentaire), Service de Nutrition, Hôpital Pitié-Salpêtrière, 75013 Paris, France.
Maithé TauberCentre de Référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et Autres Formes Rares d'Obésité avec Troubles du Comportement Alimentaire), Service d'Endocrinologie, Obésités, Maladies Osseuses, Génétique et Gynécologie Médicale, Hôpital des Enfants, 31059 Toulouse, France.
Assistance Publique – Hôpitaux de Paris · FRSorbonne Université · FRCentre National de la Recherche Scientifique · FRHôpital des Enfants · FRHôpital Necker-Enfants Malades · FRInserm · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) affects 20% of patients with Prader-Willi syndrome (PWS), with many cases diagnosed during the transition period. Our aim was to describe the natural history of T2DM in patients with PWS before the age of 25 years and to develop screening and preventive strategies. Thirty-nine patients followed in the French PWS Reference Center were included (median age 25.6 years [23.7; 31.7]). Twenty-one had been treated with growth hormone (GH), fifteen had not, and three had an unknown status. The median age at T2DM diagnosis was 16.8 years (11-24) and the median BMI was 39 kg/m

Indexed as

Prader-Willi syndromesyndromic obesitytype 2 diabetes mellitus

Identifiers

PMID34830599
PMCPMC8625265
OpenAlexW3211568796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.