Evidence map›Paper›PMID 34830576›Full record

ArticleJournal of clinical medicine2021

Risk of Suicidal Behavior in Children and Adolescents Exposed to Maltreatment: The Mediating Role of Borderline Personality Traits and Recent Stressful Life Events.

Laia Marques-Feixa, Jorge Moya-Higueras, Soledad Romero, Pilar Santamarina-Pérez, Marta Rapado-Castro, Iñaki Zorrilla, María Martín, Eulalia Anglada, María José Lobato, Maite Ramírez and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 2 countries.

Laia Marques-FeixaDepartment of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Biomedicine Institute of the University of Barcelona (IBUB), Av Diagonal 643, 2n A, 08028 Barcelona, Spain.ORCID 0000-0003-4670-5850
Jorge Moya-HiguerasNetwork Centre for Biomedical Research in Mental Health (CIBER of Mental Health, CIBERSAM), Av. Monforte de Lemos, 3-5, 28029 Madrid, Spain.ORCID 0000-0001-7017-3087
Soledad RomeroNetwork Centre for Biomedical Research in Mental Health (CIBER of Mental Health, CIBERSAM), Av. Monforte de Lemos, 3-5, 28029 Madrid, Spain.ORCID 0000-0001-9934-5196
Pilar Santamarina-PérezDepartment of Child and Adolescent Psychiatry and Psychology, 2017SGR88, Institute of Neuroscience, Hospital Clínic de Barcelona, C/Villarroel, 170, 08036 Barcelona, Spain.
Marta Rapado-CastroNetwork Centre for Biomedical Research in Mental Health (CIBER of Mental Health, CIBERSAM), Av. Monforte de Lemos, 3-5, 28029 Madrid, Spain.ORCID 0000-0001-8484-6051
Iñaki ZorrillaNetwork Centre for Biomedical Research in Mental Health (CIBER of Mental Health, CIBERSAM), Av. Monforte de Lemos, 3-5, 28029 Madrid, Spain.ORCID 0000-0001-6444-8208
María MartínAdolescent Crisis Unit, Hospital Benito Menni, C/Pablo Picasso, 12, 08830 Sant Boi de Llobregat, Spain.
Eulalia AngladaHospital for Adolescents, Fundació Orienta, c/Sant Lluís, 64, 08850 Gavà, Spain.
María José LobatoDepartment of Psychiatry, Puerta de Hierro University Hospital-Majadahonda, C/Joaquín Rodrigo, 1, 28222 Majadahonda, Spain.
Maite RamírezGaldakao Mental Health Services, Child and Adolescent Mental Health, C/Ibaizabal, 6, 48960 Galdakao, Spain.
Nerea MorenoDepartment of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Biomedicine Institute of the University of Barcelona (IBUB), Av Diagonal 643, 2n A, 08028 Barcelona, Spain.ORCID 0000-0002-4481-1724
María MayoralNetwork Centre for Biomedical Research in Mental Health (CIBER of Mental Health, CIBERSAM), Av. Monforte de Lemos, 3-5, 28029 Madrid, Spain.
María Marín-VilaDepartment of Psychiatry, Puerta de Hierro University Hospital-Majadahonda, C/Joaquín Rodrigo, 1, 28222 Majadahonda, Spain.
Bárbara AriasDepartment of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Biomedicine Institute of the University of Barcelona (IBUB), Av Diagonal 643, 2n A, 08028 Barcelona, Spain.ORCID 0000-0001-9181-2132
Lourdes FañanásDepartment of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Biomedicine Institute of the University of Barcelona (IBUB), Av Diagonal 643, 2n A, 08028 Barcelona, Spain.
Epi-Young Stress Group
Centro de Investigación Biomédica en Red de Salud Mental · ESHospital Universitario Puerta de Hierro Majadahonda · ESHospital Clínic de Barcelona · ESHospital de Galdakao · ESHospital General Universitario Gregorio Marañón · ESThe University of Melbourne · AUUniversitat de Barcelona · ESUniversitat de Lleida · ES

Funding

Agència de Gestió d'Ajuts Universitaris i de Recerca FI_B100023-2018Centro de Investigación Biomédica en Red de Salud Mental CIBERSAMDepartament d'Innovació, Universitats i Empresa, Generalitat de Catalunya 2017SGR1577Fundació Bosch i Gimpera IP: Lourdes FañanásInstituto de Salud Carlos III PI15/00097Instituto de Salud Carlos III PI15/00685Instituto de Salud Carlos III PI15/00723Instituto de Salud Carlos III PI15/00793Ministerio de Ciencia e Innovación RTI2018-099800-B-I00Ramon y Cajal research fellowship RYC-2017-23144
6 · The paper itself

Abstract

Childhood maltreatment (CM) is associated with increased non-suicidal self-injury (NSSI) and suicidal behavior (SB), independently of demographic and mental health conditions. Self-Trauma Theory and Linehan's Biopsychosocial Model might explain the emergence of Borderline Personality Disorder (BPD) symptoms as mediators of the association between CM and the risk of SB. However, little is known regarding such relationships when the exposure is recent for young persons. Here, we study 187 youths aged 7-17, with or without mental disorders. We explore CM experiences (considering the severity and frequency of different forms of neglect and abuse), recent stressful life events (SLEs), some BPD traits (emotion dysregulation, intense anger and impulsivity), and the risk of SB (including NSSI, suicide threat, suicide ideation, suicide plan and suicide attempt). We study the direct and mediating relationships between these variables via a structural equation analysis using the statistical software package EQS. Our findings suggest that youths exposed to more severe/frequent CM have more prominent BPD traits, and are more likely to have experienced recent SLEs. In turn, BPD traits increase the risk of SLEs. However, only emotion dysregulation and recent SLEs were found to be correlated with SB. Therefore, targeted interventions on emotion dysregulation are necessary to prevent NSSI or SB in children and adolescents exposed to CM, as is the minimization of further SLEs.

Indexed as

borderline personality disorder traitschildhood maltreatmentcomplex traumaemotion dysregulationnon-suicidal self-injury (NSSI)stressful life event (SLE)suicidal behavior (SB)youth

Identifiers

PMID34830576
PMCPMC8624661
OpenAlexW3214694623

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.