Evidence map›Paper›PMID 34830573›Full record

ArticleJournal of clinical medicine2021

Diaphragmatic Point-of-Care Ultrasound in COVID-19 Patients in the Emergency Department-A Proof-of-Concept Study.

Emanuele Pivetta, Irene Cara, Giulia Paglietta, Virginia Scategni, Giulia Labarile, Maria Tizzani, Giulio Porrino, Stefania Locatelli, Gilberto Calzolari, Fulvio Morello and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05805579 (Prognostic Value of Transthoracic Diaphragmatic Echography in COVID-19 Pneumonia Patients With Acute Respiratory Failure), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05805579 completednot on this map

Prognostic Value of Transthoracic Diaphragmatic Echography in COVID-19 Pneumonia Patients With Acute Respiratory Failure

TypeobservationalSponsorJavier LázaroRan2021 to 2021Enrolled171ConditionsPneumonia, Viral, Covid19, Respiratory FailureArmsDiaphragmatic echography
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
  5. Review
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Emanuele PivettaDivision of Emergency Medicine and High Dependency Unit, Città della Salute e della Scienza di Torino University Hospital, Corso Bramante 88, 10126 Turin, Italy.ORCID 0000-0003-1446-1169
Irene CaraResidency Program in Emergency Medicine, University of Turin, Via Verdi 8, 10124 Turin, Italy.
Giulia PagliettaResidency Program in Emergency Medicine, University of Turin, Via Verdi 8, 10124 Turin, Italy.ORCID 0000-0002-8899-8885
Virginia ScategniResidency Program in Emergency Medicine, University of Turin, Via Verdi 8, 10124 Turin, Italy.
Giulia LabarileResidency Program in Emergency Medicine, University of Turin, Via Verdi 8, 10124 Turin, Italy.
Maria TizzaniDivision of Emergency Medicine and High Dependency Unit, Città della Salute e della Scienza di Torino University Hospital, Corso Bramante 88, 10126 Turin, Italy.ORCID 0000-0003-3955-1224
Giulio PorrinoDivision of Emergency Medicine and High Dependency Unit, Città della Salute e della Scienza di Torino University Hospital, Corso Bramante 88, 10126 Turin, Italy.
Stefania LocatelliDivision of Emergency Medicine and High Dependency Unit, Città della Salute e della Scienza di Torino University Hospital, Corso Bramante 88, 10126 Turin, Italy.
Gilberto CalzolariDivision of Emergency Medicine and High Dependency Unit, Città della Salute e della Scienza di Torino University Hospital, Corso Bramante 88, 10126 Turin, Italy.
Fulvio MorelloDivision of Emergency Medicine and High Dependency Unit, Città della Salute e della Scienza di Torino University Hospital, Corso Bramante 88, 10126 Turin, Italy.
Milena Maria MauleDepartment of Medical Sciences, University of Turin, Corso Dogliotti 14, 10126 Turin, Italy.ORCID 0000-0003-2142-1288
Enrico LupiaDivision of Emergency Medicine and High Dependency Unit, Città della Salute e della Scienza di Torino University Hospital, Corso Bramante 88, 10126 Turin, Italy.ORCID 0000-0003-2719-1217
University of Turin · ITPiedmont Reference Center for Epidemiology and Cancer Prevention · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung Ultrasound Evaluation (LUS) is usefully applied in the Emergency Department (ED) to patients with suspected or confirmed COVID-19. Diaphragmatic Ultrasound (DUS) may provide additional insight into ventilatory function. This proof-of-concept study aimed to evaluate the feasibility of LUS and DUS in a third level ED during the COVID-19 pandemic.

methodsAdult patients presenting with COVID-19 symptoms were eligible. After the physical examination, both LUS and DUS (i.e., diaphragmatic motion and thickness) were performed. All patients were followed after 30 days to determine their need for ventilation, admission, and/or a new ED evaluation after discharge. The diagnostic accuracies of diaphragm measurements in assessing the risk of the 30-day outcome were calculated as well as the measurements' usefulness. Bland-Altman plots were used for comparing bedside and off-line diaphragm measurements.

results118 patients were enrolled. Median thickness and motion were 1.7 mm (iqr 0.4) and 1.8 cm (iqr 0.7), respectively, with a mean difference of 0.009 mm (95% CI -0.037-0.056 mm) and -0.051 cm (95% CI -0.108-0.006 cm), respectively. The 30-day outcome was associated with an increase in thickness (OR 5.84, 95% CI 0.96-35.4), and a lower motion (OR 0.49, 95% CI 0.2-1.21).

conclusionDUS seemed to be feasible and reliable in the ED in a population of patients presenting with symptoms related to COVID-19 infection.

Indexed as

COVID-19diaphragmpoint-of-care ultrasound

Identifiers

PMID34830573
PMCPMC8623129
OpenAlexW3213295540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.