Evidence map›Paper›PMID 34830458›Full record

ArticleInternational journal of molecular sciences2021

Effects of Training Status and Exercise Mode on Global Gene Expression in Skeletal Muscle.

Daniel A Bizjak, Martina Zügel, Gunnar Treff, Kay Winkert, Achim Jerg, Jens Hudemann, Frank C Mooren, Karsten Krüger, Andreas Nieß, Jürgen M Steinacker

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniel A BizjakDivision of Sports and Rehabilitation Medicine, Department of Internal Medicine II, University of Ulm, 89075 Ulm, Germany.ORCID 0000-0003-4075-0204
Martina ZügelDivision of Sports and Rehabilitation Medicine, Department of Internal Medicine II, University of Ulm, 89075 Ulm, Germany.
Gunnar TreffDivision of Sports and Rehabilitation Medicine, Department of Internal Medicine II, University of Ulm, 89075 Ulm, Germany.ORCID 0000-0001-5388-4282
Kay WinkertDivision of Sports and Rehabilitation Medicine, Department of Internal Medicine II, University of Ulm, 89075 Ulm, Germany.
Achim JergDivision of Sports and Rehabilitation Medicine, Department of Internal Medicine II, University of Ulm, 89075 Ulm, Germany.
Jens HudemannDepartment of Sports Medicine, University Hospital Tübingen, 72074 Tübingen, Germany.
Frank C MoorenDepartment of Medicine, Faculty of Health, University of Witten/Herdecke, 58455 Witten, Germany.
Karsten KrügerDepartment of Exercise Physiology and Sports Therapy, University of Gießen, 35394 Gießen, Germany.
Andreas NießDepartment of Sports Medicine, University Hospital Tübingen, 72074 Tübingen, Germany.
Jürgen M SteinackerDivision of Sports and Rehabilitation Medicine, Department of Internal Medicine II, University of Ulm, 89075 Ulm, Germany.ORCID 0000-0001-8901-9450

Funding

Bundesinstitut für Sportwissenschaft 62000369
6 · The paper itself

Abstract

The aim of this study was to investigate differences in skeletal muscle gene expression of highly trained endurance and strength athletes in comparison to untrained individuals at rest and in response to either an acute bout of endurance or strength exercise. Endurance (ET,

Indexed as

AthletesAdolescentAdultExercise TestGene Expression RegulationHumansHypoxia-Inducible Factor 1, alpha SubunitInsulin Receptor Substrate ProteinsMaleMuscle, SkeletalMyostatinPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPhysical EnduranceProtein Array AnalysisResistance TrainingRNA, MessengerHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitInsulin Receptor Substrate ProteinsIRS1 protein, humanIRS2 protein, humanMSTN protein, humanMyostatinPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPPARGC1A protein, humanRNA, MessengerVascular Endothelial Growth Factor Aendurance exercisemicroarraymolecular muscle adaptationspathway analysisstrength exercisetraining statustranscriptional regulation

Identifiers

PMID34830458
PMCPMC8674764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.