Evidence map›Paper›PMID 34830420›Full record

ArticleInternational journal of molecular sciences2021

Chemoenzymatic Synthesis and Antibody Binding of HIV-1 V1/V2 Glycopeptide-Bacteriophage Q

Guanghui Zong, Christian Toonstra, Qiang Yang, Roushu Zhang, Lai-Xi Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Guanghui ZongDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0002-7335-039X
Christian ToonstraDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Qiang YangDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Roushu ZhangDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Lai-Xi WangDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
University of Maryland, College Park · US

Funding

Synthetic HIV Vaccine Targeting Glycopeptide Neutralizing EpitopesR01AI113896 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI WANG, LAI-XI · 2014 to 2018
$2.3M
NIH HHS R01 AI113896
6 · The paper itself

Abstract

The broadly neutralizing antibody PG9 recognizes a unique glycopeptide epitope in the V1V2 domain of HIV-1 gp120 envelope glycoprotein. The present study describes the design, synthesis, and antibody-binding analysis of HIV-1 V1V2 glycopeptide-Q

Indexed as

AIDS VaccinesAllolevivirusAntibodies, NeutralizingAntigensEpitopesGlycopeptidesHIV-1HIV Envelope Protein gp120HIV InfectionsHumansPeptide FragmentsPhagocytosisAIDS VaccinesAntibodies, NeutralizingAntigensEpitopesGlycopeptidesHIV Envelope Protein gp120HIV envelope protein gp120 (135-148)Peptide Fragmentsbacteriophage QβglycoconjugateglycopeptideHIV vaccineneutralizing antibodyneutralizing epitope

Identifiers

PMID34830420
PMCPMC8617853
OpenAlexW3215598047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.