Evidence map›Paper›PMID 34830409›Full record

ArticleInternational journal of molecular sciences2021

Trabecular Bone Parameters, TIMP-2, MMP-8, MMP-13, VEGF Expression and Immunolocalization in Bone and Cartilage in Newborn Offspring Prenatally Exposed to Fumonisins.

Ewa Tomaszewska, Halyna Rudyk, Izabela Świetlicka, Monika Hułas-Stasiak, Janine Donaldson, Marta Arczewska, Siemowit Muszyński, Piotr Dobrowolski, Maria Mielnik-Błaszczak, Marcin Bartłomiej Arciszewski and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. 17β-Estradiol Maintains Mitochondrial Homeostasis in Osteoblasts by Inhibiting MMP-8 and Activating the Ras Signaling Pathway in Postmenopausal Osteoporosis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Ewa TomaszewskaDepartment of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Akademicka St. 12, 20-950 Lublin, Poland.ORCID 0000-0002-7574-2653
Halyna RudykState Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Donetska St. 11, 79000 Lviv, Ukraine.ORCID 0000-0002-4152-560X
Izabela ŚwietlickaDepartment of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, Akademicka St. 13, 20-950 Lublin, Poland.ORCID 0000-0003-1053-0948
Monika Hułas-StasiakDepartment of Functional Anatomy and Cytobiology, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, 19 Akademicka St., 20-033 Lublin, Poland.ORCID 0000-0002-5039-009X
Janine DonaldsonSchool of Physiology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg 2193, South Africa.ORCID 0000-0001-5072-016X
Marta ArczewskaDepartment of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, Akademicka St. 13, 20-950 Lublin, Poland.ORCID 0000-0003-2553-0908
Siemowit MuszyńskiDepartment of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, Akademicka St. 13, 20-950 Lublin, Poland.ORCID 0000-0002-4118-6302
Piotr DobrowolskiDepartment of Functional Anatomy and Cytobiology, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, 19 Akademicka St., 20-033 Lublin, Poland.ORCID 0000-0001-5873-9666
Maria Mielnik-BłaszczakChair and Department of Developmental Dentistry, Medical University of Lublin, 7 Karmelicka St., 20-081 Lublin, Poland.
Marcin Bartłomiej ArciszewskiDepartment of Animal Anatomy and Histology, University of Life Sciences in Lublin, 20-950 Lublin, Poland.ORCID 0000-0002-3643-3524
Volodymyr KushnirState Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Donetska St. 11, 79000 Lviv, Ukraine.
Oksana BrezvynState Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Donetska St. 11, 79000 Lviv, Ukraine.
Viktor MuzykaState Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Donetska St. 11, 79000 Lviv, Ukraine.
Ihor KotsyumbasState Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Donetska St. 11, 79000 Lviv, Ukraine.
SCIVP of Veterinary Medicinal Products and Feed Additives · UAUniversity of Life Sciences in Lublin · PLMaria Curie-Skłodowska University · PLMedical University of Lublin · PLUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fumonisins are protein serine/threonine phosphatase inhibitors and potent inhibitors of sphingosine N-acyltransferase (ceramide synthase) disrupting de novo sphingolipid biosynthesis. The experiment was conducted to evaluate the effects of fumonisins (FB) exposure from the 7th day of pregnancy to parturition on offspring bone development. The rats were randomly allocated to either a control group (

Indexed as

AnimalsAnimals, NewbornBone DevelopmentCancellous BoneCartilageFemaleFumonisinsGene Expression Regulation, DevelopmentalGrowth PlateMatrix Metalloproteinase 13Matrix Metalloproteinase 8OxidoreductasesPregnancyRatsSphingolipidsTissue Inhibitor of Metalloproteinase-2dihydroceramide desaturaseFumonisinsMatrix Metalloproteinase 13Matrix Metalloproteinase 8Mmp8 protein, ratOxidoreductasesSphingolipidsTimp2 protein, ratTissue Inhibitor of Metalloproteinase-2Vascular Endothelial Growth Factor Avascular endothelial growth factor A, ratarticular cartilagebonefumonisins (FB)matrix metalloproteinase 13 (MMP-13)matrix metalloproteinase 8 (MMP-8)newborn ratstissue inhibitor of metalloproteinases 2 (TIMP-2)

Identifiers

PMID34830409
PMCPMC8623786
OpenAlexW3217114792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.