Evidence map›Paper›PMID 34830382›Full record

ArticleInternational journal of molecular sciences2021

Upregulated Guanine Deaminase Is Involved in Hyperpigmentation of Seborrheic Keratosis via Uric Acid Release.

Kyung Ah Cheong, In Sup Kil, Hyuk Wan Ko, Ai-Young Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Kyung Ah CheongDepartment of Dermatology, Dongguk University Ilsan Hospital, 814 Siksa-dong, Ilsandong-gu, Goyang-si 410-773, Gyeonggi-do, Korea.
In Sup KilBasic Research & Innovation Division, Amorepacific Corporation R&D Center, Yongin-si 446-729, Gyeonggi-do, Korea.
Hyuk Wan KoDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.ORCID 0000-0003-1753-1900
Ai-Young LeeDepartment of Dermatology, Dongguk University Ilsan Hospital, 814 Siksa-dong, Ilsandong-gu, Goyang-si 410-773, Gyeonggi-do, Korea.
Dongguk University Ilsan Hospital · KRAmorepacific (South Korea) · KRYonsei University · KR

Funding

Korea Health Industry Development Institute HP20C0131National Research Foundation of Korea NRF 2018R1A5A2023127
6 · The paper itself

Abstract

Seborrheic keratosis, which is a benign tumor composed of epidermal keratinocytes, develops common in the elderly. Uric acid generated by upregulated guanine deaminase (

Indexed as

AgedCells, CulturedEpidermal CellsFemaleGene Expression Regulation, EnzymologicGuanine DeaminaseHumansHyperpigmentationKeratinocytesKeratosis, SeborrheicMaleMelanocytesMiddle AgedSkinUric AcidGuanine DeaminaseUric AcidGDAhyperpigmentationphotoagingseborrheic keratosisuric acid

Identifiers

PMID34830382
PMCPMC8625227
OpenAlexW3216500252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.