Evidence map›Paper›PMID 34830381›Full record

ReviewInternational journal of molecular sciences2021

Non-Cell Autonomous and Epigenetic Mechanisms of Huntington's Disease.

Chaebin Kim, Ali Yousefian-Jazi, Seung-Hye Choi, Inyoung Chang, Junghee Lee, Hoon Ryu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Neuronal Calcium Signaling and Cytoskeletal Dynamics in Neurodegeneration.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Molecular Research on Huntington's Disease.International journal of molecular sciences · 2023
    Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Chaebin KimBrain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.
Ali Yousefian-JaziBrain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.
Seung-Hye ChoiBrain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.
Inyoung ChangDepartment of Biology, Boston University, Boston, MA 02215, USA.
Junghee LeeBoston University Alzheimer's Disease Research Center, Boston University, Boston, MA 02118, USA.
Hoon RyuBrain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.ORCID 0000-0001-6544-3732
Korea Institute of Brain Science · KRBoston University · US

Funding

Modulation of neuronal atrophy in Huntington's diseaseR01NS109537 · NINDS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LEE, JUNGHEE · 2018 to 2022
$1.4M
Korea Institute of Science and Technology 2E30954Korea Institute of Science and Technology 2E30962National Research Council of Science and Technology CRC-15-04-KISTNational Research Foundation of Korea NRF-2018M3C7A1056894National Research Foundation of Korea NRF-2020M3E5D9079742NIH HHS R01AG054156NIH HHS R01NS109537NINDS NIH HHS R01 NS109537
6 · The paper itself

Abstract

Huntington's disease (HD) is a rare neurodegenerative disorder caused by an expansion of CAG trinucleotide repeat located in the exon 1 of

Indexed as

Epigenesis, GeneticAnimalsBrainCorpus StriatumDisease Models, AnimalHumansHuntingtin ProteinHuntington DiseaseNeostriatumNerve Tissue ProteinsNeuronsHuntingtin ProteinNerve Tissue ProteinsastrocyteepigeneticsHuntington’s diseasemitochondria dysfunctionnon-cell autonomous pathwayoligodendrocytetherapeutic targetsvesicle trafficking

Identifiers

PMID34830381
PMCPMC8617801
OpenAlexW3217117065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.