Evidence map›Paper›PMID 34830253›Full record

ArticleInternational journal of molecular sciences2021

Human Epidermal Zinc Concentrations after Topical Application of ZnO Nanoparticles in Sunscreens.

Zahra Khabir, Amy M Holmes, Yi-Jen Lai, Liuen Liang, Anand Deva, Michael A Polikarpov, Michael S Roberts, Andrei V Zvyagin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Zahra KhabirDepartment of Physics and Astronomy & Earth and Planetary Sciences & Clinical Medicine, Macquarie University, Sydney 2109, Australia.ORCID 0000-0003-0094-1647
Amy M HolmesClinical Health Sciences and Basil Hetzel Institute for Translational Health Research, University of South Australia, Adelaide 5000, Australia.
Yi-Jen LaiDepartment of Physics and Astronomy & Earth and Planetary Sciences & Clinical Medicine, Macquarie University, Sydney 2109, Australia.
Liuen LiangDepartment of Physics and Astronomy & Earth and Planetary Sciences & Clinical Medicine, Macquarie University, Sydney 2109, Australia.
Anand DevaDepartment of Physics and Astronomy & Earth and Planetary Sciences & Clinical Medicine, Macquarie University, Sydney 2109, Australia.
Michael A PolikarpovNational Research Centre "Kurchatov Institute", Moscow 123098, Russia.
Michael S RobertsClinical Health Sciences and Basil Hetzel Institute for Translational Health Research, University of South Australia, Adelaide 5000, Australia.ORCID 0000-0003-3894-5301
Andrei V ZvyaginDepartment of Physics and Astronomy & Earth and Planetary Sciences & Clinical Medicine, Macquarie University, Sydney 2109, Australia.ORCID 0000-0001-8799-2257
ARC Centre for Nanoscale BioPhotonicsMacquarie University · AUKurchatov Institute · RUSechenov University · RUThe University of Queensland · AUUniversity of South Australia · AU

Funding

National Health and Medical Research Council 1107356Russian Foundation for Basic Research 20-04-00182
6 · The paper itself

Abstract

Zinc oxide nanoparticle (ZnO NP)-based sunscreens are generally considered safe because the ZnO NPs do not penetrate through the outermost layer of the skin, the stratum corneum (SC). However, cytotoxicity of zinc ions in the viable epidermis (VE) after dissolution from ZnO NP and penetration into the VE is ill-defined. We therefore quantified the relative concentrations of endogenous and exogenous Zn using a rare stable zinc-67 isotope (

Indexed as

AbdominoplastyAdministration, CutaneousCell LineCell SurvivalEpidermisFemaleFluoresceinsFluorescent DyesHumansKeratinocytesMetal NanoparticlesMicroscopy, Fluorescence, MultiphotonMiddle AgedNanoparticlesQuinolonesSkin AbsorptionFluoresceinsFluorescent DyesQuinolonesSunscreening AgentsTosyl CompoundsZinc Oxidezinpyr-1zinquinepidermal zincisotope tracingmultiphoton microscopynanotoxicologyZnO nanoparticles

Identifiers

PMID34830253
PMCPMC8618668
OpenAlexW3212057753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.