Evidence map›Paper›PMID 34830191›Full record

ArticleInternational journal of molecular sciences2021

The Effect of Oxidative Stress and Memantine-Incorporated Reactive Oxygen Species-Sensitive Nanoparticles on the Expression of

Jung Sun Park, Taeyeon Kim, Dohoon Kim, Young-Il Jeong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Jung Sun ParkDepartment of Internal Medicine, Chonnam National University Medical School, 42 Jebongro, Gwangju 61469, Korea.
Taeyeon KimCollege of Art&Science, University of Pennsylvania, 249 S 36th St., Philadelphia, PA 19104, USA.
Dohoon KimDepartment of Integrative Physiology and Pathobiology, Tufts University School of Medicine, Boston, MA 02111, USA.
Young-Il JeongResearch Institute of Convergence of Biomedical Sciences, Pusan National University Yangsan Hospital, Yangsan 50612, Korea.
Chonnam National University · KRPusan National University Yangsan Hospital · KRTufts University · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to fabricate reactive oxygen species (ROS)-sensitive nanoparticles composed of succinyl β-cyclodextrin (bCDsu), memantine and thioketal linkages for application in Alzheimer's disease, and to investigate the suppression of

Indexed as

Alzheimer DiseaseAnimalsBrain NeoplasmsCell Line, TumorCell SurvivalDrug Delivery SystemsDrug LiberationHumansMaleMemantineMiceMice, Inbred BALB CMice, NudeNanoparticlesNerve Tissue ProteinsNeuroblastomaGRIN1 protein, humanMemantineNerve Tissue ProteinsN-MethylaspartateReactive Oxygen SpeciesReceptors, N-Methyl-D-AspartateAlzheimer’s diseasecyclodextrin nanoparticlesmemantinereactive oxygen speciesROS-sensitive drug delivery

Identifiers

PMID34830191
PMCPMC8619842
OpenAlexW3213111161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.