Evidence map›Paper›PMID 34830187›Full record

ArticleInternational journal of molecular sciences2021

Ammonium Formate-Pd/C as a New Reducing System for 1,2,4-Oxadiazoles. Synthesis of Guanidine Derivatives and Reductive Rearrangement to Quinazolin-4-Ones with Potential Anti-Diabetic Activity.

Paola Marzullo, Sonya Vasto, Silvestre Buscemi, Andrea Pace, Domenico Nuzzo, Antonio Palumbo Piccionello

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Bioactive Oxadiazoles 2.0.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Paola MarzulloDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche-STEBICEF, Università degli Studi di Palermo, 90128 Palermo, Italy.
Sonya VastoDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche-STEBICEF, Università degli Studi di Palermo, 90128 Palermo, Italy.ORCID 0000-0002-6033-4745
Silvestre BuscemiDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche-STEBICEF, Università degli Studi di Palermo, 90128 Palermo, Italy.
Andrea PaceDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche-STEBICEF, Università degli Studi di Palermo, 90128 Palermo, Italy.ORCID 0000-0003-1992-2024
Domenico NuzzoDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche-STEBICEF, Università degli Studi di Palermo, 90128 Palermo, Italy.ORCID 0000-0002-4325-417X
Antonio Palumbo PiccionelloDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche-STEBICEF, Università degli Studi di Palermo, 90128 Palermo, Italy.ORCID 0000-0003-4402-5798
University of Palermo · ITInstituto di Biofisica · ESIstituto Euro Mediterraneo di Scienza e Tecnologia · IT

Funding

Ministry of Education, Universities and Research RBFR12SIPT
6 · The paper itself

Abstract

1,2,4-Oxadiazole is a heterocycle with wide reactivity and many useful applications. The reactive O-N bond is usually reduced using molecular hydrogen to obtain amidine derivatives. NH

Indexed as

A549 Cellsalpha-GlucosidasesAntineoplastic AgentsCell Line, TumorCell SurvivalDiabetes MellitusDipeptidyl Peptidase 4FormatesGuanidinesHumansHypoglycemic AgentsModels, ChemicalMolecular StructureOxadiazolesOxidation-ReductionPalladium4-hydroxyquinazolinealpha-GlucosidasesAntineoplastic AgentsDipeptidyl Peptidase 4Formatesformic acidGuanidinesHypoglycemic AgentsOxadiazolesPalladiumQuinazolinones1,2,4-oxadiazoleacylguanidineammonium formatediacylguanidinepalladiumquinazolin-4-onereduction

Identifiers

PMID34830187
PMCPMC8621334
OpenAlexW3214174055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.