Evidence map›Paper›PMID 34830091›Full record

ArticleInternational journal of molecular sciences2021

The Effects of Flavonoid Apigenin on Male Reproductive Health: Inhibition of Spermatogonial Proliferation through Downregulation of

Bingyuan Wang, Mingrui Zhang, Jiankang Guo, Zhiguo Liu, Rong Zhou, Fei Guo, Kui Li, Yulian Mu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Examining the combined benefits of photobiomodulation and apigenin for the treatment of asthenozoospermia: An innovative therapeutic strategy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Life (Basel, Switzerland) · 2022
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bingyuan WangInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Mingrui ZhangInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Jiankang GuoInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Zhiguo LiuInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.ORCID 0000-0003-0599-9039
Rong ZhouInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Fei GuoCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Kui LiInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Yulian MuInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Chinese Academy of Agricultural Sciences · CNAgricultural Genomics Institute at Shenzhen · CNChina Agricultural University · CN

Funding

Agricultural Science and Technology Innovation Program ASTIP-IAS05National Natural Science Foundation of China 31702083National Transgenic Breeding Project 2016ZX08006001Special Fund of Chinese Central Government for Basic Scientific Research Operations in Com-monweal Research Institutes 2020-YWF-YB-06
6 · The paper itself

Abstract

Apigenin, a common dietary flavonoid abundantly present in a variety of fruits and vegetables, has promising anticancer properties. As an effector of apigenin in myoblasts, protein arginine methyltransferase 7 (

Indexed as

AnimalsApigeninCell ProliferationDown-RegulationGene Expression Regulation, EnzymologicMaleMiceMice, Inbred ICRProtein-Arginine N-MethyltransferasesProto-Oncogene Proteins c-aktReproductive HealthSignal TransductionSpermatogoniaAkt3 protein, mouseApigeninPRMT7 protein, mouseProtein-Arginine N-MethyltransferasesProto-Oncogene Proteins c-aktAkt3apigeninmousePrmt7spermatogonial proliferation

Identifiers

PMID34830091
PMCPMC8621337
OpenAlexW3214299219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.