ArticleInternational journal of molecular sciences2021
Steroid-Functionalized Imidazolium Salts with an Extended Spectrum of Antifungal and Antibacterial Activity.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Anticancer Properties of Imidazolium Salt Derivatives: Current Advances and Therapeutic Perspectives.Cancers · 2026Review
- Lithocholic Acid-Derived Imidazolium Salts Suppress Breast Cancer Growth: In Vitro and In Vivo Evaluation.Pharmaceutical research · 2026Article
- Functionalized Ionic Liquids at Bacterial Membrane Interfaces: A Multiscale Perspective from Tensiometry, Microscopy, and Molecular Dynamics.The journal of physical chemistry. B · 2026Article
- Synthesis and antitumor activity of steroid-based imidazolium salts.RSC advances · 2025Article
- Acetylphenyl-substituted imidazolium salts: synthesis, characterization, in silico studies and inhibitory properties against some metabolic enzymes.Molecular diversity · 2023Article
- Synthetic and Natural Antifungals-Desirable and Hazardous Effects.International journal of molecular sciences · 2022Article
- Establishment of In Vitro and In Vivo Anticolorectal Cancer Efficacy of Lithocholic Acid-Based Imidazolium Salts.International journal of molecular sciences · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is established that high rates of morbidity and mortality caused by fungal infections are related to the current limited number of antifungal drugs and the toxicity of these agents. Imidazolium salts as azole derivatives can be successfully used in the treatment of fungal infections in humans. Steroid-functionalized imidazolium salts were synthesized using a new, more efficient method. As a result, 20 salts were obtained with high yields, 12 of which were synthesized and characterized for the first time. They were derivatives of lithocholic acid and 3-oxo-23,24-dinorchol-4-ene-22-al and were fully characterized by
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Registered trials
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