Evidence map›Paper›PMID 34830021›Full record

ArticleInternational journal of molecular sciences2021

Optimized Synthesis of New Thiosemicarbazide Derivatives with Tuberculostatic Activity.

Corina Popovici, Cristina-Maria Pavel, Valeriu Sunel, Corina Cheptea, Dan Gheorghe Dimitriu, Dana Ortansa Dorohoi, Diana David, Valentina Closca, Marcel Popa

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. New Drugs and Novel Cellular Targets against Tuberculosis.International journal of molecular sciences · 2022
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Corina PopoviciFaculty of Chemistry, Alexandru Ioan Cuza University, 11 Carol I Blvd., 700506 Iasi, Romania.
Cristina-Maria PavelFaculty of Physics, Alexandru Ioan Cuza University, 11 Carol I Blvd., 700506 Iasi, Romania.ORCID 0000-0002-0941-1856
Valeriu SunelFaculty of Chemistry, Alexandru Ioan Cuza University, 11 Carol I Blvd., 700506 Iasi, Romania.
Corina ChepteaDepartment of Biomedical Sciences, Faculty of Medical Bioengineering, "Grigore T. Popa" University of Medicine and Pharmacy, 9-13 M. Kogalniceanu Str., 700454 Iasi, Romania.
Dan Gheorghe DimitriuFaculty of Physics, Alexandru Ioan Cuza University, 11 Carol I Blvd., 700506 Iasi, Romania.ORCID 0000-0002-2474-5133
Dana Ortansa DorohoiFaculty of Physics, Alexandru Ioan Cuza University, 11 Carol I Blvd., 700506 Iasi, Romania.
Diana DavidWarwick Medical School, University of Warwick, Coventry CV4 7AL, UK.ORCID 0000-0002-0637-1684
Valentina CloscaFaculty of Physics, Alexandru Ioan Cuza University, 11 Carol I Blvd., 700506 Iasi, Romania.
Marcel PopaDepartment of Natural and Synthetic Polymers, Faculty of Chemical Engineering and Environmental Protection, "Gheorghe Sachi" Technical University, 73 Professor Dimitrie Mangeron Blvd., 700050 Iasi, Romania.ORCID 0000-0003-4929-0830
Alexandru Ioan Cuza University · ROGheorghe Asachi Technical University of Iași · ROGrigore T. Popa University of Medicine and Pharmacy · ROUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Original results are presented in the field of research that addresses the extension of the reaction of residue of acyl-thiosemicarbazide fixation on the structure of 5-nitrobenzimidazole by a sulphonic group. The aim of the study is the increase of new thiosemicarbazide derivatives' applicative potential in the field of biochemistry, with a wide range of medical applications. The newly obtained compounds were characterized by using elemental analysis and spectral analysis (FT-IR and

Indexed as

Antitubercular AgentsHumansMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsMycobacterium tuberculosisSemicarbazidesSpectroscopy, Fourier Transform InfraredStructure-Activity RelationshipTuberculosisAntitubercular AgentsSemicarbazidesthiosemicarbazide2-mercapto-benzimidazoleheterocyclic thiosemicarbazidessulfonic derivativestuberculostatic activity

Identifiers

PMID34830021
PMCPMC8622382
OpenAlexW3214703216

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.