Evidence map›Paper›PMID 34829994›Full record

ArticleInternational journal of molecular sciences2021

Estrogens Regulate Placental Angiogenesis in Horses.

Shingo Haneda, Pouya Dini, Alejandro Esteller-Vico, Kirsten E Scoggin, Edward L Squires, Mats H Troedsson, Peter Daels, Yasuo Nambo, Barry A Ball

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Cells · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Shingo HanedaDepartment of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan.
Pouya DiniGluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546, USA.ORCID 0000-0001-5553-5967
Alejandro Esteller-VicoGluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546, USA.
Kirsten E ScogginGluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546, USA.ORCID 0000-0003-1348-641X
Edward L SquiresGluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546, USA.
Mats H TroedssonGluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546, USA.
Peter DaelsFaculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.ORCID 0000-0001-7884-0307
Yasuo NamboDepartment of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan.
Barry A BallGluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546, USA.ORCID 0000-0002-0502-0276
University of Kentucky · USObihiro University of Agriculture and Veterinary Medicine · JPGhent University · BE

Funding

the Albert G. Clay Endowment and the Clay Visiting Scholar Fellowship of the University of Kentucky
6 · The paper itself

Abstract

A sufficient vascular network within the feto-maternal interface is necessary for placental function. Several pregnancy abnormalities have been associated with abnormal vascular formations in the placenta. We hypothesized that growth and expansion of the placental vascular network in the equine (

Indexed as

AndrostenedioneAngiopoietin-1AnimalsAromataseEstrogensFemaleGene Expression Regulation, DevelopmentalHorsesLetrozoleMaternal-Fetal RelationsNeovascularization, PhysiologicPlacentaPregnancyPregnancy Trimester, FirstReceptors, AndrogenSteroid 17-alpha-HydroxylaseAndrostenedioneAngiopoietin-1AromataseEstrogensLetrozoleReceptors, AndrogenSteroid 17-alpha-HydroxylaseTestosteroneVascular Endothelial Growth Factor A17β-estradiolangiogenesischorioallantoisequineestrogenletrozoleplacentaplacental developmentpregnancy

Identifiers

PMID34829994
PMCPMC8621320
OpenAlexW3212202900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.