Evidence map›Paper›PMID 34829929›Full record

ReviewBiomedicines2021

Applications of Plasma-Activated Liquid in the Medical Field.

Sungryeal Kim, Chul-Ho Kim

Registry-linked trialAbstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05924867 (Application of Plasma Activated Saline in Wound Treatment), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05924867 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Application of Plasma Activated Saline in Wound Treatment

TypeinterventionalSponsorFirst Affiliated Hospital Xi'an Jiaotong UniversityRan2023 to 2024Enrolled162ConditionsWound, Wound Infection, Wound HealArmsplasma activated saline, Routine nursing
3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Argon plasma-activated liquid inactivatesFrontiers in microbiology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Plasma-Activated Water Against Carbapenem-ResistantPathogens (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sungryeal KimDepartment of Otolaryngology, School of Medicine, Ajou University, Suwon 16499, Korea.
Chul-Ho KimDepartment of Otolaryngology, School of Medicine, Ajou University, Suwon 16499, Korea.

Funding

Korea Health Industry Development Institute HR21C1003National Research Foundation of Korea 2017M3A9F7079339
6 · The paper itself

Abstract

Much progress has been made since plasma was discovered in the early 1900s. The first form of plasma was thermal type, which was limited for medical use due to potential thermal damage on living cells. In the late 1900s, with the development of a nonthermal atmospheric plasma called cold plasma, profound clinical research began and 'plasma medicine' became a new area in the academic field. Plasma began to be used mainly for environmental problems, such as water purification and wastewater treatment, and subsequent research on plasma and liquid interaction led to the birth of 'plasma-activated liquid' (PAL). PAL is currently used in the fields of environment, food, agriculture, nanoparticle synthesis, analytical chemistry, and sterilization. In the medical field, PAL usage can be expanded for accessing places where direct application of plasma is difficult. In this review, recent studies with PAL will be introduced to inform researchers of the application plan and possibility of PAL in the medical field.

Indexed as

cold plasmaplasma-activated liquidplasma-activated water

Identifiers

PMID34829929
PMCPMC8615748

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.