Evidence map›Paper›PMID 34829867›Full record

ArticleBiomedicines2021

LncRNAs LY86-AS1 and VIM-AS1 Distinguish Plasma Cell Leukemia Patients from Multiple Myeloma Patients.

Romana Bútová, Petra Vychytilová-Faltejsková, Jana Gregorová, Lenka Radová, Martina Almáši, Renata Bezděková, Lucie Brožová, Jiří Jarkovský, Zdeňka Knechtová, Martin Štork and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Romana BútováBabak Myeloma Group, Department of Pathophysiology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
Petra Vychytilová-FaltejskováBabak Myeloma Group, Department of Pathophysiology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0003-3881-3536
Jana GregorováBabak Myeloma Group, Department of Pathophysiology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
Lenka RadováDepartment of Molecular Medicine, Central European Institute of Technology (CEITEC), Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0001-8103-148X
Martina AlmášiDepartment of Clinical Hematology, University Hospital Brno, 625 00 Brno, Czech Republic.
Renata BezděkováDepartment of Clinical Hematology, University Hospital Brno, 625 00 Brno, Czech Republic.ORCID 0000-0001-8427-0750
Lucie BrožováInstitute of Biostatistics and Analyses (IBA), Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
Jiří JarkovskýInstitute of Biostatistics and Analyses (IBA), Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
Zdeňka KnechtováClinic of Internal Medicine, Hematology and Oncology, University Hospital Brno, 625 00 Brno, Czech Republic.
Martin ŠtorkClinic of Internal Medicine, Hematology and Oncology, University Hospital Brno, 625 00 Brno, Czech Republic.
Luděk PourClinic of Internal Medicine, Hematology and Oncology, University Hospital Brno, 625 00 Brno, Czech Republic.
Sabina ŠevčíkováBabak Myeloma Group, Department of Pathophysiology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0002-7194-6771
Masaryk University · CZUniversity Hospital Brno · CZCentral European Institute of Technology · CZ

Funding

Ministry of Education Youth and Sports MUNI/A/1698/2020Ministry of Health FNBr 65269705Ministry of Health NV18-03-00203
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) are functional RNAs longer than 200 nucleotides. Due to modern genomic techniques, the involvement of lncRNAs in tumorigenesis has been revealed; however, information concerning lncRNA interplay in multiple myeloma (MM) and plasma cell leukemia (PCL) is virtually absent. Herein, we aimed to identify the lncRNAs involved in MM to PCL progression. We investigated representative datasets of MM and PCL patients using next-generation sequencing. In total, 13 deregulated lncRNAs (

Indexed as

biomarkersdisease progressionlong non-coding RNAmultiple myelomanext-generation sequencingplasma cell leukemia

Identifiers

PMID34829867
PMCPMC8615960
OpenAlexW3212854229

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.