ArticleBiomedicines2021
Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin.
Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Clinical performance of an alkasite-based bioactive restorative in class II cavities: a randomized clinical trial.Journal of applied oral science : revista FOB · 2023Trial
- Performance of an alkasite restorative material under acidic conditions: surface roughness, gloss and hardness.Scientific reports · 2026Article
- Repair Bond Strength of Ion-Releasing Versus Conventional Resin Composites.Materials (Basel, Switzerland) · 2026Article
- Article
- The Effect of Different pH and Temperature Values on CaPolymers · 2025Article
- Calcium, phosphate and fluoride ionic release from dental restorative materials for elderly population: anFrontiers in oral health · 2025Article
- Effect of customized bioactive glass in experimental composites on dentin bond strength after 12 months of aging.Clinical oral investigations · 2024Article
- Mechanical Properties of Alkasite Material with Different Curing Modes and Simulated Aging Conditions.Materials (Basel, Switzerland) · 2024Article
- Water-Induced Changes in Experimental Resin Composites Functionalized with Conventional (45S5) and Customized Bioactive Glass.Journal of functional biomaterials · 2023Article
- Bioactivity Potential of Bioceramic-Based Root Canal Sealers: A Scoping Review.Life (Basel, Switzerland) · 2022Article
- A Narrative Review of Bioactive Glass-Loaded Dental Resin Composites.Journal of functional biomaterials · 2022Review
- Using Copper-Doped Mesoporous Bioactive Glass Nanospheres to Impart Anti-Bacterial Properties to Dental Composites.Pharmaceutics · 2022Article
- Improved Flexural Properties of Experimental Resin Composites Functionalized with a Customized Low-Sodium Bioactive Glass.Polymers · 2022Article
- Effect of adhesive coating on calcium, phosphate, and fluoride release from experimental and commercial remineralizing dental restorative materials.Scientific reports · 2022Article
- Long-Term Assessment of Contemporary Ion-Releasing Restorative Dental Materials.Materials (Basel, Switzerland) · 2022Article
- The Effect of a Green Smoothie on Microhardness, Profile Roughness and Color Change of Dental Restorative Materials.Polymers · 2022Article
- Comparison of the effect of preheating on the flexural strength of giomer and nanohybrid composite resin.Journal of dental research, dental clinics, dental prospects · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
The purpose of this in vitro study was to investigate whether different types of experimental and commercial restorative dental materials can protect dentin against acid-induced softening. Experimental composites were prepared with a photocurable mixture of methacrylates and two types of bioactive glass (45S5 and a customized low-Na F-containing formulation). Human dentin samples were prepared from mid-coronal tooth slices and immersed in lactic acid solution (pH = 4.0) at 5 mm from set specimens of restorative material. After 4, 8, 12, 16, 20, 24, 28, and 32 days, surface microhardness of dentin samples and pH of the immersion solution were measured, followed by replenishing of the immersion medium. Microstructural analysis was performed using scanning electron microscopy. The protective effect of restorative materials was determined as dentin microhardness remaining statistically similar to initial values for a certain number of acid additions. Scanning electron microscopy showed a gradual widening of dentinal tubules and proved less discriminatory than microhardness measurements. To produce a protective effect on dentin, 20 wt% of low-Na F-containing bioactive glass was needed, whereas 10 wt% of bioactive glass 45S5 was sufficient to protect dentin against acid-induced demineralization. The anti-demineralizing protective effect of experimental and commercial restoratives on dentin was of shorter duration than measured for enamel in a previous study using the same experimental approach.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.