Evidence map›Paper›PMID 34829835›Full record

ArticleBiomedicines2021

Comparative Analysis of Dental Pulp and Periodontal Stem Cells: Differences in Morphology, Functionality, Osteogenic Differentiation and Proteome.

Anastasia V Kotova, Arseniy A Lobov, Julia A Dombrovskaya, Valentina Y Sannikova, Nadezhda A Ryumina, Polina Klausen, Alexey L Shavarda, Anna B Malashicheva, Natella I Enukashvily

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
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  9. Mutanobactin-D, aInternational journal of molecular sciences · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. TheJournal of dental sciences · 2024
    Article
  16. Article
  17. Research progress of dental pulp regeneration treatment.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Anastasia V KotovaInstitute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.
Arseniy A LobovInstitute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.ORCID 0000-0002-0930-1171
Julia A DombrovskayaCell Technologies Laboratory, General Dentistry Department, North-Western State Medical University, 191015 St. Petersburg, Russia.
Valentina Y SannikovaInstitute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.ORCID 0000-0003-4861-4805
Nadezhda A RyuminaCell Technologies Center Pokrovsky, LLC, 199106 St. Petersburg, Russia.
Polina KlausenInstitute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.
Alexey L ShavardaResearch Resource Center Molecular and Cell Technologies, Saint-Petersburg State University, 199034 St. Petersburg, Russia.
Anna B MalashichevaInstitute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.ORCID 0000-0002-0820-2913
Natella I EnukashvilyInstitute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.ORCID 0000-0002-5971-7917
Institute of Cytology · RUSt Petersburg University · RU

Funding

Ministry of Health of Russian Federation State assignment No. 056-00056-19-00 (theme No АААА-А18-118052990081)Russian Foundation for Basic Research 19-29-04082
6 · The paper itself

Abstract

Dental stem cells are heterogeneous in their properties. Despite their common origin from neural crest stem cells, they have different functional capacities and biological functions due to niche influence. In this study, we assessed the differences between dental pulp stem cells (DPSC) and periodontal ligament stem cells (PDLSC) in their pluripotency and neuroepithelial markers transcription, morphological and functional features, osteoblast/odontoblast differentiation and proteomic profile during osteogenic differentiation. The data were collected in paired observations: two cell cultures, DPSC and PDLSC, were obtained from each donor. Both populations had the mesenchymal stem cells surface marker set exposed on their membranes but differed in

Indexed as

dental pulp stem cellsdental stem cellsmass-spectrometryodontoblastic differentiationosteogenic differentiationperiodontal ligament stem cellspluripotencyproteomicssomatic OCT4SSEA-4

Identifiers

PMID34829835
PMCPMC8616025
OpenAlexW3208912071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.