Evidence map›Paper›PMID 34829823›Full record

ReviewBiomedicines2021

Neoplastic Implications in Patients Suffering from Hidradenitis Suppurativa under Systemic Treatments.

Federica Li Pomi, Laura Macca, Alfonso Motolese, Ylenia Ingrasciotta, Massimiliano Berretta, Claudio Guarneri

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Federica Li PomiDepartment of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 1-98125 Messina, Italy.ORCID 0000-0001-6760-9468
Laura MaccaDepartment of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 1-98125 Messina, Italy.ORCID 0000-0001-6470-8751
Alfonso MotoleseDepartment of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 1-98125 Messina, Italy.ORCID 0000-0002-1383-4165
Ylenia IngrasciottaDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Pharmacology, University of Messina, 1-98125 Messina, Italy.
Massimiliano BerrettaDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Infectious Diseases, University of Messina, 1-98125 Messina, Italy.ORCID 0000-0002-9837-9148
Claudio GuarneriDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Dermatology, University of Messina, 1-98125 Messina, Italy.ORCID 0000-0003-3918-8779
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease of the apocrine glands. It typically involves the axillary, submammary, genital, inguinal, perineal, and perianal regions. The development of abscesses, sinus tracts, and scars can lead to pain, scarring, disfigurement and decreased quality of life. HS is associated with a wide range of comorbidities. Several studies of co-occurrence of HS and nonmelanoma skin cancer suggest a causal relationship. In an attempt to assess the link between HS and cancer, we performed a systematic review of the current scientific knowledge through a PubMed-based literature search. Results show that HS could be associated with an overall risk of cancer and numerous specific cancers such as: nonmelanoma skin cancer (NMSC), hematologic malignancies, and metastatic cancer. Among NMSC, squamous cell carcinoma (SCC) is considered the most common complication arising in long-standing HS. Based on our review, we suggest that cautious surveillance and active intervention may be warranted in patients with HS. Moreover, an age-appropriate cancer screening should be offered to all patients, especially those who developed HS later in their life or in long-standing moderate to severe HS with multiple comorbidities.

Indexed as

cancercutaneous tumourshaematological malignancieshidradenitis suppurativaHS treatmentnoncutaneous tumours

Identifiers

PMID34829823
PMCPMC8615387
OpenAlexW3211106370

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.