Evidence map›Paper›PMID 34829776›Full record

ArticleBiomedicines2021

Stable Gastric Pentadecapeptide BPC 157 as a Therapy for the Disable Myotendinous Junctions in Rats.

Mladen Japjec, Katarina Horvat Pavlov, Andreja Petrovic, Mario Staresinic, Bozidar Sebecic, Matko Buljan, Hrvoje Vranes, Ana Giljanovic, Domagoj Drmic, Miroslav Japjec and 8 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Myotendinous Junction development and repair.Journal of orthopaedic translation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Mladen JapjecDepartment of Surgery, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Katarina Horvat PavlovDepartment of Pathology, School of Medicine, University of Zagreb, P.O. Box 910, Salata 10, 10000 Zagreb, Croatia.
Andreja PetrovicDepartment of Pathology, School of Medicine, University of Zagreb, P.O. Box 910, Salata 10, 10000 Zagreb, Croatia.
Mario StaresinicDepartment of Surgery, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Bozidar SebecicDepartment of Surgery, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Matko BuljanDepartment of Pharmacology, School of Medicine, University of Zagreb, P.O. Box, 916, Salata 11, 10000 Zagreb, Croatia.
Hrvoje VranesDepartment of Pharmacology, School of Medicine, University of Zagreb, P.O. Box, 916, Salata 11, 10000 Zagreb, Croatia.
Ana GiljanovicDepartment of Pharmacology, School of Medicine, University of Zagreb, P.O. Box, 916, Salata 11, 10000 Zagreb, Croatia.ORCID 0000-0002-9447-0526
Domagoj DrmicDepartment of Pharmacology, School of Medicine, University of Zagreb, P.O. Box, 916, Salata 11, 10000 Zagreb, Croatia.
Miroslav JapjecDepartment of Pharmacology, School of Medicine, University of Zagreb, P.O. Box, 916, Salata 11, 10000 Zagreb, Croatia.
Andreja PrtoricDepartment of Surgery, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Eva LovricDepartment of Pathology, School of Medicine, University of Zagreb, P.O. Box 910, Salata 10, 10000 Zagreb, Croatia.
Lovorka Batelja VuleticDepartment of Pathology, School of Medicine, University of Zagreb, P.O. Box 910, Salata 10, 10000 Zagreb, Croatia.
Ivan DobricDepartment of Surgery, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Alenka Boban BlagaicDepartment of Pharmacology, School of Medicine, University of Zagreb, P.O. Box, 916, Salata 11, 10000 Zagreb, Croatia.
Anita SkrticDepartment of Pathology, School of Medicine, University of Zagreb, P.O. Box 910, Salata 10, 10000 Zagreb, Croatia.ORCID 0000-0002-9275-7283
Sven SeiwerthDepartment of Pathology, School of Medicine, University of Zagreb, P.O. Box 910, Salata 10, 10000 Zagreb, Croatia.
Sikiric PredragDepartment of Pharmacology, School of Medicine, University of Zagreb, P.O. Box, 916, Salata 11, 10000 Zagreb, Croatia.
University of Zagreb · HR

Funding

Sveučilište u Zagrebu 099
6 · The paper itself

Abstract

(1) Aim: The stable gastric pentadecapeptide BPC 157 is known to heal transected muscle, tendon, and ligament. Thereby, in this study, we investigated the effect of BPC 157 on the dissection of the quadriceps tendon from the quadriceps muscle in rats. (2) Materials and Methods: Myotendinous junction defect, which cannot heal spontaneously in rats, as evidenced with consistent macro/microscopic, biomechanical, functional assessments,

Indexed as

BPC 157 therapyleg contracturemyotendinous junctionsnitric oxideoxidative stresswalking recovery index

Identifiers

PMID34829776
PMCPMC8615275
OpenAlexW3209425377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.