Evidence map›Paper›PMID 34829739›Full record

ArticleBiomedicines2021

Plasma Lipoprotein(a) Levels as Determinants of Arterial Stiffening in Hypertension.

Gabriele Brosolo, Andrea Da Porto, Luca Bulfone, Antonio Vacca, Nicole Bertin, Gianluca Colussi, Alessandro Cavarape, Leonardo A Sechi, Cristiana Catena

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Lipoprotein(a) Does Not Correlate with Hypertensive Mediated Organ Damage and Subsequent Cardiovascular Events in a Primary Prevention Cohort.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  2. Article
  3. Lipoprotein(a) in Essential Hypertension: Associations with Blood Pressure and Hypertension-Mediated Organ Damage.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Observational
  4. Article
  5. Article
  6. Review
  7. Serum Lipoprotein(a) Levels as a Predictor of Aortic Stiffness in Patients on Long-Term Peritoneal Dialysis.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  8. Article
  9. Article
  10. Lipoprotein(a): Just an Innocent Bystander in Arterial Hypertension?International journal of molecular sciences · 2023
    Review
  11. Article
  12. The Impact of the Blood Lipids Levels on Arterial Stiffness.Journal of cardiovascular development and disease · 2023
    Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Gabriele BrosoloClinica Medica, Department of Medicine, University of Udine, 33100 Udine, Italy.
Andrea Da PortoClinica Medica, Department of Medicine, University of Udine, 33100 Udine, Italy.
Luca BulfoneClinica Medica, Department of Medicine, University of Udine, 33100 Udine, Italy.
Antonio VaccaClinica Medica, Department of Medicine, University of Udine, 33100 Udine, Italy.ORCID 0000-0003-0051-7723
Nicole BertinClinica Medica, Department of Medicine, University of Udine, 33100 Udine, Italy.
Gianluca ColussiClinica Medica, Department of Medicine, University of Udine, 33100 Udine, Italy.ORCID 0000-0003-1673-540X
Alessandro CavarapeClinica Medica, Department of Medicine, University of Udine, 33100 Udine, Italy.ORCID 0000-0003-2726-5714
Leonardo A SechiClinica Medica, Department of Medicine, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-6242-0209
Cristiana CatenaClinica Medica, Department of Medicine, University of Udine, 33100 Udine, Italy.
University of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have shown that plasma lipoprotein(a) (Lp(a)) plays an important role in the development of hypertensive organ damage. The aim of the present study was to investigate the relationship of Lp(a) with markers of arterial stiffening in hypertension. In 138 essential hypertensive patients free of diabetes, renal failure and cardiovascular complications, we measured plasma lipids and assessed vascular stiffness through the use of pulse wave analysis and calculation of the brachial augmentation index (AIx), and measured the pulse wave velocity (PWV). Plasma Lp(a) levels were significantly and directly related to both AIx (

Indexed as

arterial stiffnessaugmentation indexhypertensionlipoprotein(a)pulse wave velocity

Identifiers

PMID34829739
PMCPMC8615029
OpenAlexW3205563962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.