Evidence map›Paper›PMID 34829722›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Immunomodulation and Antioxidant Activities as Possible Trypanocidal and Cardioprotective Mechanisms of Major Terpenes from

Denerieth Ximena Espinel-Mesa, Clara Isabel González Rugeles, Julio César Mantilla Hernández, Elena E Stashenko, Carlos Andrés Villegas-Lanau, John Jaime Quimbaya Ramírez, Liliana Torcoroma García Sánchez

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trypanocidal Activity of Crude Extracts fromJournal of fungi (Basel, Switzerland) · 2026
    Article
  2. Plant-Derived Terpenes as Emerging Therapeutics Against Schistosomiasis.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Journal of fungi (Basel, Switzerland) · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Denerieth Ximena Espinel-MesaInfectious Diseases Postgraduate Program, Instituto de Investigación Masira, Universidad de Santander, Bucaramanga 680006, Santander, Colombia.ORCID 0000-0003-1961-6844
Clara Isabel González RugelesImmunology and Molecular Epidemiology Group, School of Microbiology, Universidad Industrial de Santander, Bucaramanga 680002, Santander, Colombia.
Julio César Mantilla HernándezPathology Department, School of Medicine, Universidad Industrial de Santander, Bucaramanga 680002, Santander, Colombia.
Elena E StashenkoNational Research Center for the Agroindustrialization of Tropical Aromatic and Medicinal Plant Species-CENIVAM, Universidad Industrial de Santander, Bucaramanga 680002, Santander, Colombia.ORCID 0000-0001-7052-932X
Carlos Andrés Villegas-LanauNeurosciences Group of Antioquia, Brain Bank, Universidad de Antioquia, Medellín 050010, Antioquia, Colombia.
John Jaime Quimbaya RamírezInfectious Diseases Postgraduate Program, Instituto de Investigación Masira, Universidad de Santander, Bucaramanga 680006, Santander, Colombia.
Liliana Torcoroma García SánchezInfectious Diseases Postgraduate Program, Instituto de Investigación Masira, Universidad de Santander, Bucaramanga 680006, Santander, Colombia.ORCID 0000-0001-9054-9328
Industrial University of Santander · COUniversidad De Santander · COUniversidad de Antioquia · CO

Funding

Ministry of National Education, Ministry of Industry, Commerce and Tourism and ICETEX, call for scientific ecosystem - Scientific Colombia. Francisco José de Caldas Fund RC-FP44842-212-2018the Vicerrectoría de Investigaciones-Universidad de Santander UDES 001-18
6 · The paper itself

Abstract

In the late phase of

Indexed as

antioxidantcaryophyllene oxidechronic Chagas diseaseessential oilsimmunohistochemistryimmunomodulationlimoneneLippia albaTrypanosoma cruzi

Identifiers

PMID34829722
PMCPMC8614928
OpenAlexW3216392317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.