Evidence map›Paper›PMID 34829700›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Phenolic Compounds in Calafate Berries Encapsulated by Spray Drying: Neuroprotection Potential into the Ingredient.

María E Romero-Román, Mauricio Schoebitz, Jorge Fuentealba, Cristina García-Viguera, María D López Belchí

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Calafate (Antioxidants (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

María E Romero-RománDepartamento de Producción Vegetal, Facultad de Agronomía, Universidad de Concepción, Vicente Méndez #595, Chillán 3812120, Chile.ORCID 0000-0003-2665-5366
Mauricio SchoebitzDepartamento de Suelos y Recursos Naturales, Facultad de Agronomía, Universidad de Concepción, Víctor Lamas 1290, Concepción 4030000, Chile.ORCID 0000-0003-3953-8425
Jorge FuentealbaDepartamento de Fisiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Víctor Lamas 1290, Concepción 4030000, Chile.
Cristina García-VigueraPhytochemistry & Healthy Foods Lab (LabFAS), Department Food Science & Technology, CEBAS-CSIC, Campus de Espinardo 25, Espinardo, 30100 Murcia, Spain.ORCID 0000-0002-4751-3917
María D López BelchíDepartamento de Producción Vegetal, Facultad de Agronomía, Universidad de Concepción, Vicente Méndez #595, Chillán 3812120, Chile.ORCID 0000-0002-5490-5871

Funding

FONDECYT 1160899
6 · The paper itself

Abstract

Calafate is a berry rich in anthocyanins that presents higher content of polyphenols than other fruits. Its compounds have been described previously, however, the potential thereof in preventing and treating degenerative disorders has not yet been studied. Due to its astringency, the consumption of this berry in its natural state is limited. To profit from the aforementioned properties and reduce palatability issues, calafate berry extracts were microencapsulated by spray drying, a rapid, cost-effective and scalable process, and were then compared with freeze drying as a control. The stability of its contents and its in-vitro potential, with respect to AChE activity and neuroprotection, were measured from the obtained microcapsules, resulting from temperature treatments and different encapsulant contents. The results indicated that the spray-dried powders were stable, despite high temperatures, and their encapsulation exhibited nearly 50% efficiency. The highest quantity of polyphenols and 3-

Indexed as

anthocyaninsBerberis microphyllaencapsulationnext generation ingredientsPC12 cells

Identifiers

PMID34829700
PMCPMC8614940

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.