Evidence map›Paper›PMID 34829668›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Impact of Fennel Essential Oil as an Antibiotic Alternative in Rabbit Diet on Antioxidant Enzymes Levels, Growth Performance, and Meat Quality.

Tharwat Imbabi, Islam Sabeq, Ali Osman, Kamal Mahmoud, Shimaa A Amer, Aziza M Hassan, Nikolay Kostomakhin, Walid Habashy, Ahmed A Easa

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 91 citations in OpenAlex.

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  10. Review
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  12. Dietary Supplementation withAnimals : an open access journal from MDPI · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Tharwat ImbabiDepartment of Animal Production, Faculty of Agriculture, Benha Univerisity, Benha 13736, Egypt.ORCID 0000-0002-6975-1393
Islam SabeqDepartment of Food Hygiene, Faculty of Veterinary Medicine, Benha University, Benha 13736, Egypt.ORCID 0000-0002-7516-7265
Ali OsmanBiochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.
Kamal MahmoudBiochemistry Department, Faculty of Agriculture, Menoufia University, Shibin El-Kom 32511, Egypt.
Shimaa A AmerDepartment of Nutrition & Clinical Nutrition, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt.ORCID 0000-0002-8349-0425
Aziza M HassanDepartment of Biotechnology, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.ORCID 0000-0002-0406-412X
Nikolay KostomakhinDepartment of Dairy and Beef Cattle Breeding, Russian State Agrarian University-Moscow Agriculture Academy, 115432 Moscow, Russia.
Walid HabashyFaculty of Agriculture, Animal and Poultry Production, Damanhour University, Damanhour 22511, Egypt.
Ahmed A EasaFaculty of Agriculture, Animal and Poultry Production, Damanhour University, Damanhour 22511, Egypt.
Benha University · EGDamanhour University · EGZagazig University · EGMenoufia University · EGMoscow State Agroengineering University named after V.P. Goryachkin · RUTaif University · SA

Funding

Taif University Research Supporting Project, Taif University, Taif, Saudi Arabia (TURSP-2020/76)
6 · The paper itself

Abstract

In the current study, fennel essential oil was used as an antibiotic alternative compared to gentamycin for enhancing the expression of apoptosis genes and antioxidant enzymes in weaned rabbits as well as meat quality and growth performance. The gene expression of the cell lymphoma 2 (BAX and BCL2), caspase3 (CASP3), and glutathione peroxidase (GPX1) were estimated in the liver tissue using qRT-PCR. A total of 45 Moshtohor weaned male rabbits aged four weeks were randomly allocated to control, T1, and T2 treatment groups; each consisted of 15 weaned male rabbits with five replicates. Rabbits in the T1 and T2 groups were orally supplied with 1 mL fennel oil and 1 mL gentamycin, respectively. Weaned rabbits under different treatments showed increased body weight (BW) at 8 and 12 weeks of age and average daily gain (ADG) at 4-8 and 4-12 weeks of age compared to the control group. Compared to the controls, the weaned rabbits supplemented with fennel oil and gentamycin had lower total cholesterol, triglyceride, and MDA. In addition, villus length, mRNA of BAX, BCL2, Casp3, and GPX were increased in the different treatments compared to the control. Furthermore, the meat of these rabbits was less tender, had a lower aerobic plate count (APC), pH, and was brighter and redder in color than the control. Under the conditions of the present study, the supplementation of weaned Moshtohor rabbits with fennel oil as a natural alternative for gentamycin enhanced feed conversion and daily gain through enhancing villus length and mucus thickness. Additionally, fennel essential oil reduces oxidative stress by increasing the antioxidant enzymes.

Indexed as

apoptosisfennel oilgene expressionmeat qualityweaned rabbits

Identifiers

PMID34829668
PMCPMC8614930
OpenAlexW3214120544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.