Evidence map›Paper›PMID 34829502›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Controlling Droplet Marangoni Flows to Improve Microscopy-Based TB Diagnosis.

Stephanie I Pearlman, Eric M Tang, Yuankai K Tao, Frederick R Haselton

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stephanie I PearlmanDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA.ORCID 0000-0003-3909-1088
Eric M TangDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Yuankai K TaoDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Frederick R HaseltonDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA.ORCID 0000-0003-4282-5222
Vanderbilt University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Training Program for Innovative Engineering Research in Surgery and InterventionT32EB021937 · NIBIB · VANDERBILT UNIVERSITY · PI Dario J Englot, Michael Ian Miga · 2016 to 2026
$2.3M
Intraoperative Optical Coherence Tomography for Ophthalmic Surgical GuidanceR01EY030490 · NEI · VANDERBILT UNIVERSITY · PI TAO, YUANKAI KENNY · 2019 to 2023
$1.8M
A 100-fold more sensitive TB diagnostic based on magnetic concentration and "coffee ring" formationR01AI135937 · NIAID · VANDERBILT UNIVERSITY · PI BLACKBURN, JONATHAN MICHAEL, HASELTON, FREDERICK R · 2017 to 2021
$1.7M
Intraoperative imaging of macular hole repair to predict visual function outcomesR01EY031769 · NEI · VANDERBILT UNIVERSITY · PI TAO, YUANKAI KENNY · 2020 to 2023
$1.4M
NCI NIH HHS P30 CA068485NEI NIH HHS R01 EY030490NEI NIH HHS R01 EY031769NIAID NIH HHS R01 AI135937NIBIB NIH HHS T32 EB021937NIDDK NIH HHS P30 DK058404NIH HHS R01-AI135937NIH HHS R01-EY030490NIH HHS R01-EY031769
6 · The paper itself

Abstract

In developing countries, the most common diagnostic method for tuberculosis (TB) is microscopic examination sputum smears. Current assessment requires time-intensive inspection across the microscope slide area, and this contributes to its poor diagnostic sensitivity of ≈50%. Spatially concentrating TB bacteria in a smaller area is one potential approach to improve visual detection and potentially increase sensitivity. We hypothesized that a combination of magnetic concentration and induced droplet Marangoni flow would spatially concentrate

Indexed as

acid-fastcoffee ringlow-resourceMarangoni flowmicroscopynanoparticlepoint-of-care diagnosissputum smeartuberculosisZiehl–Neelsen

Identifiers

PMID34829502
PMCPMC8618690
OpenAlexW3215555435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.