Evidence map›Paper›PMID 34829491›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Multidisciplinary In-Depth Investigation in a Young Athlete Suffering from Syncope Caused by Myocardial Bridge.

Mariarita Brancaccio, Cristina Mennitti, Arturo Cesaro, Emanuele Monda, Valeria D'Argenio, Giorgio Casaburi, Cristina Mazzaccara, Annaluisa Ranieri, Fabio Fimiani, Ferdinando Barretta and 10 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Cripto Is Targeted by miR-1a-3p in a Mouse Model of Heart Development.International journal of molecular sciences · 2023
    Article
  6. Article
  7. Identification ofDiagnostics (Basel, Switzerland) · 2022
    Article
  8. Myocardial Bridging Leading to Cardiac Collapse in a Marathon Runner.Journal of cardiovascular development and disease · 2022
    Article
  9. Identification of aMedicina (Kaunas, Lithuania) · 2022
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Mariarita BrancaccioDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-4161-512X
Cristina MennittiDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-6355-5976
Arturo CesaroDepartment of Translational Medical Sciences, Università degli Studi della Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-4435-1235
Emanuele MondaDepartment of Translational Medical Sciences, Università degli Studi della Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0001-9304-988X
Valeria D'ArgenioCeinge Biotecnologie Avanzate S. C. a R. L., 80131 Naples, Italy.ORCID 0000-0001-9273-3698
Giorgio CasaburiPrescient Metabiomics, 1600 Faraday Ave, Carlsbad, CA 9200, USA.
Cristina MazzaccaraDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-7774-2799
Annaluisa RanieriCeinge Biotecnologie Avanzate S. C. a R. L., 80131 Naples, Italy.
Fabio FimianiUnit of Inherited and Rare Cardiovascular Diseases, Azienda Ospedaliera di Rilievo Nazionale AORN Dei Colli, "V. Monaldi", 80122 Naples, Italy.
Ferdinando BarrettaDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
Fabiana UomoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
Martina CaiazzaInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", Monaldi Hospital, 81100 Naples, Italy.ORCID 0000-0003-3805-4170
Michele LioncinoDepartment of Translational Medical Sciences, Università degli Studi della Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Giovanni D'AlicandroDepartment of Neuroscience and Rehabilitation, Center of Sports Medicine and Disability, AORN, Santobono-Pausillipon, 80122 Naples, Italy.
Giuseppe LimongelliDepartment of Translational Medical Sciences, Università degli Studi della Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-8291-9517
Paolo CalabròDepartment of Translational Medical Sciences, Università degli Studi della Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-5018-830X
Daniela TerraccianoDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-4296-429X
Barbara LombardoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-3884-1043
Giulia FrissoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-3487-7743
Olga ScudieroDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-4916-4976
Ceinge Biotecnologie Avanzate (Italy) · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Naples Federico II · ITOspedale Monaldi · ITSan Raffaele University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laboratory medicine, along with genetic investigations in sports medicine, is taking on an increasingly important role in monitoring athletes' health conditions. Acute or intense exercise can result in metabolic imbalances, muscle injuries or reveal cardiovascular disorders. This study aimed to monitor the health status of a basketball player with an integrated approach, including biochemical and genetic investigations and advanced imaging techniques, to shed light on the causes of recurrent syncope he experienced during exercise. Biochemical analyses showed that the athlete had abnormal iron, ferritin and bilirubin levels. Coronary Computed Tomographic Angiography highlighted the presence of an intramyocardial bridge, suggesting this may be the cause of the observed syncopes. The athlete was excluded from competitive activity. In order to understand if this cardiac malformation could be caused by an inherited genetic condition, both array-CGH and whole exome sequencing were performed. Array-CGH showed two intronic deletions involving

Indexed as

athleteexome sequencinggenomic analysisheart bridgelaboratory medicineoligogenic combination networksport activity

Identifiers

PMID34829491
PMCPMC8618222
OpenAlexW3217122270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.