Evidence map›Paper›PMID 34829430›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Optical Biosensors for Diagnostics of Infectious Viral Disease: A Recent Update.

Atul Sharma, Rupesh Kumar Mishra, K Yugender Goud, Mona A Mohamed, Shekher Kummari, Swapnil Tiwari, Zhanhong Li, Roger Narayan, Lia A Stanciu, Jean Louis Marty

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 74 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 5 countries.

Atul SharmaDepartment of Pharmaceutical Chemistry, SGT College of Pharmacy, SGT University, Budhera, Gurugram 122505, Haryana, India.ORCID 0000-0003-0877-1275
Rupesh Kumar MishraBindley Bio-Science Center, Lab 222, 1203 W. State St., Purdue University, West Lafayette, IN 47907, USA.
K Yugender GoudDepartment of NanoEngineering, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-0530-0489
Mona A MohamedPharmaceutical Chemistry Department, National Organization for Drug Control and Research (NODCAR), Egyptian Drug Authority, Giza 99999, Egypt.ORCID 0000-0003-2721-5725
Shekher KummariDepartment of Chemistry, National Institute of Technology, Warangal 506004, Telangana, India.
Swapnil TiwariSchool of Studies in Chemistry, Pt. Ravishankar Shukla University, Raipur 492010, Chattisgarh, India.ORCID 0000-0003-3589-0974
Zhanhong LiSchool of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, 516 Jungong Road, Yangpu District, Shanghai 200093, China.ORCID 0000-0002-3552-7545
Roger NarayanDepartment of Materials Science and Engineering, NC State University, Raleigh, NC 27695, USA.ORCID 0000-0002-4876-9869
Lia A StanciuSchool of Materials Engineering, Purdue University, 701 West Stadium Avenue, West Lafayette, IN 47907, USA.
Jean Louis MartyBAE-LBBM Laboratory, University of Perpignan via Domitia, 52 Avenue Paul Alduy, CEDEX 9, 66860 Perpignan, France.
Purdue University West Lafayette · USNational Institute of Technology Warangal · INNational Organization for Drug Control and Research · EGNorth Carolina State University · USPandit Ravishankar Shukla University · INShree Guru Gobind Singh Tricentenary University · INUniversité de Perpignan · FRUniversity of California San Diego · USUniversity of Shanghai for Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The design and development of biosensors, analytical devices used to detect various analytes in different matrices, has emerged. Biosensors indicate a biorecognition element with a physicochemical analyzer or detector, i.e., a transducer. In the present scenario, various types of biosensors have been deployed in healthcare and clinical research, for instance, biosensors for blood glucose monitoring. Pathogenic microbes are contributing mediators of numerous infectious diseases that are becoming extremely serious worldwide. The recent outbreak of COVID-19 is one of the most recent examples of such communal and deadly diseases. In efforts to work towards the efficacious treatment of pathogenic viral contagions, a fast and precise detection method is of the utmost importance in biomedical and healthcare sectors for early diagnostics and timely countermeasures. Among various available sensor systems, optical biosensors offer easy-to-use, fast, portable, handy, multiplexed, direct, real-time, and inexpensive diagnosis with the added advantages of specificity and sensitivity. Many progressive concepts and extremely multidisciplinary approaches, including microelectronics, microelectromechanical systems (MEMSs), nanotechnologies, molecular biology, and biotechnology with chemistry, are used to operate optical biosensors. A portable and handheld optical biosensing device would provide fast and reliable results for the identification and quantitation of pathogenic virus particles in each sample. In the modern day, the integration of intelligent nanomaterials in the developed devices provides much more sensitive and highly advanced sensors that may produce the results in no time and eventually help clinicians and doctors enormously. This review accentuates the existing challenges engaged in converting laboratory research to real-world device applications and optical diagnostics methods for virus infections. The review's background and progress are expected to be insightful to the researchers in the sensor field and facilitate the design and fabrication of optical sensors for life-threatening viruses with broader applicability to any desired pathogens.

Indexed as

diagnosticsfluorescencenanomaterialoptical biosensorsSARS-CoV-2viral disease

Identifiers

PMID34829430
PMCPMC8625106
OpenAlexW3212579796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.