Evidence map›Paper›PMID 34829396›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Automation of Lung Ultrasound Interpretation via Deep Learning for the Classification of Normal versus Abnormal Lung Parenchyma: A Multicenter Study.

Robert Arntfield, Derek Wu, Jared Tschirhart, Blake VanBerlo, Alex Ford, Jordan Ho, Joseph McCauley, Benjamin Wu, Jason Deglint, Rushil Chaudhary and 4 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  19. New International Guidelines and Consensus on the Use of Lung Ultrasound.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Robert ArntfieldDivision of Critical Care Medicine, Western University, London, ON N6A 5C1, Canada.
Derek WuSchulich School of Medicine and Dentistry, Western University, London, ON N6A 5C1, Canada.
Jared TschirhartSchulich School of Medicine and Dentistry, Western University, London, ON N6A 5C1, Canada.ORCID 0000-0003-1313-350X
Blake VanBerloFaculty of Mathematics, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
Alex FordIndependent Researcher, London, ON N6A 1L8, Canada.
Jordan HoSchulich School of Medicine and Dentistry, Western University, London, ON N6A 5C1, Canada.
Joseph McCauleyFaculty of Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
Benjamin WuIndependent Researcher, London, ON N6C 4P9, Canada.
Jason DeglintFaculty of Systems Design Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
Rushil ChaudharySchulich School of Medicine and Dentistry, Western University, London, ON N6A 5C1, Canada.
Chintan DaveDivision of Critical Care Medicine, Western University, London, ON N6A 5C1, Canada.
Bennett VanBerloFaculty of Engineering, University of Western Ontario, London, ON N6A 5C1, Canada.
John BasmajiDivision of Critical Care Medicine, Western University, London, ON N6A 5C1, Canada.
Scott MillingtonDepartment of Critical Care Medicine, University of Ottawa, Ottawa, ON K1N 6N5, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung ultrasound (LUS) is an accurate thoracic imaging technique distinguished by its handheld size, low-cost, and lack of radiation. User dependence and poor access to training have limited the impact and dissemination of LUS outside of acute care hospital environments. Automated interpretation of LUS using deep learning can overcome these barriers by increasing accuracy while allowing point-of-care use by non-experts. In this multicenter study, we seek to automate the clinically vital distinction between A line (normal parenchyma) and B line (abnormal parenchyma) on LUS by training a customized neural network using 272,891 labelled LUS images. After external validation on 23,393 frames, pragmatic clinical application at the clip level was performed on 1162 videos. The trained classifier demonstrated an area under the receiver operating curve (AUC) of 0.96 (±0.02) through 10-fold cross-validation on local frames and an AUC of 0.93 on the external validation dataset. Clip-level inference yielded sensitivities and specificities of 90% and 92% (local) and 83% and 82% (external), respectively, for detecting the B line pattern. This study demonstrates accurate deep-learning-enabled LUS interpretation between normal and abnormal lung parenchyma on ultrasound frames while rendering diagnostically important sensitivity and specificity at the video clip level.

Indexed as

artificial intelligenceautomationdeep learningimaginglung ultrasoundultrasound

Identifiers

PMID34829396
PMCPMC8621216

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.