Evidence map›Paper›PMID 34829358›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Is Primary HPV with Secondary p16/Ki67 Dual-Stain an Alternative HSIL-Risk Detection Strategy in Cervical Cancer Screening for Women under 30 Years?

Martyna Trzeszcz, Maciej Mazurec, Robert Jach, Karolina Mazurec, Zofia Jach, Izabela Kotkowska-Szeps, Magdalena Kania, Mariola Wantuchowicz, Anna Prokopyk, Piotr Barcikowski and 3 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Clinical and Virological Profiles Associated with CINTECDiagnostics (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Martyna TrzeszczCorfamed Woman's Health Center, Kluczborska 37, 50-322 Wroclaw, Poland.ORCID 0000-0002-9971-1093
Maciej MazurecCorfamed Woman's Health Center, Kluczborska 37, 50-322 Wroclaw, Poland.ORCID 0000-0003-2152-157X
Robert JachDivision of Gynecologic Endocrinology, Jagiellonian University Medical College, Kopernika 23, 31-501 Krakow, Poland.
Karolina MazurecCorfamed Woman's Health Center, Kluczborska 37, 50-322 Wroclaw, Poland.
Zofia JachSuperior Medical Center, Czyzynska 21/50, 31-571 Krakow, Poland.
Izabela Kotkowska-SzepsCorfamed Woman's Health Center, Kluczborska 37, 50-322 Wroclaw, Poland.
Magdalena KaniaCorfamed Woman's Health Center, Kluczborska 37, 50-322 Wroclaw, Poland.
Mariola WantuchowiczCorfamed Woman's Health Center, Kluczborska 37, 50-322 Wroclaw, Poland.
Anna ProkopykCorfamed Woman's Health Center, Kluczborska 37, 50-322 Wroclaw, Poland.
Piotr BarcikowskiCorfamed Woman's Health Center, Kluczborska 37, 50-322 Wroclaw, Poland.
Marcin PrzybylskiDepartment of Obstetrics and Gynecology, District Public Hospital, Juraszow 7-19, 60-479 Poznan, Poland.
Joanna WachCorfamed Woman's Health Center, Kluczborska 37, 50-322 Wroclaw, Poland.
Agnieszka HalonDepartment of Clinical and Experimental Pathology, Division of Clinical Pathology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland.
Woman's Hospital · USJagiellonian University · PLWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, cervical cancer rates elevation has been noted in women aged 20-39 years in regions with a very high human development index (HDI). The onset of cancer elevation rates is observed in the age range of 25-29 years, which should necessitate effective precancer screening in younger age groups, including those <25 years. From 30.066 liquid-based screening tests results (

Indexed as

cancer biomarkerscervical cancer screeningCINtec PLUShigh-risk HPVHPV DNAp16/Ki67 dual-staintriageyoung women

Identifiers

PMID34829358
PMCPMC8624363
OpenAlexW3209943356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.