Evidence map›Paper›PMID 34829306›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Platelet Activation and Inflammation in Patients with Papillary Thyroid Cancer.

Sorina Martin, Theodor Mustata, Oana Enache, Oana Ion, Andreea Chifulescu, Anca Sirbu, Carmen Barbu, Adrian Miron, Cosmin Giulea, Florin Andrei and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sorina MartinEndocrinology Department, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0001-9622-8883
Theodor MustataEndocrinology Department, Elias Hospital, 011461 Bucharest, Romania.ORCID 0000-0001-6522-4361
Oana EnacheEndocrinology Department, Elias Hospital, 011461 Bucharest, Romania.
Oana IonNephrology Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Andreea ChifulescuGastroenterology Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Anca SirbuEndocrinology Department, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0003-3659-4544
Carmen BarbuEndocrinology Department, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Adrian MironSurgery Department, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Cosmin GiuleaSurgery Department, Elias Hospital, 011461 Bucharest, Romania.
Florin AndreiPathology Department, Elias Hospital, 011461 Bucharest, Romania.
Simona FicaEndocrinology Department, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · ROInstitutul Clinic Fundeni · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe primary endpoint was to analyze the preoperatory inflammatory markers and platelet indices in papillary thyroid cancer (PTC) patients compared with patients with benign thyroid pathology. The secondary endpoints were to analyze the relationship between these markers and the pathological features of PTC and to compare their pre- and postoperative levels in PTC patients.

methodsIn this retrospective case-control study, we analyzed the files of 1183 patients submitted to thyroidectomy between January 2012 and December 2018. A total of 234 patients with PTC (mean age 51.54 ± 13.10 years, 84.6% females) were compared with an age-, gender- and BMI-matched control group of 108 patients with histologic benign thyroid disorders.

resultsPTC patients had higher platelet count (PLT) (

conclusionsOur data show that fibrinogen and platelet count could be promising, inexpensive, independent predictors for the presence of PTC when compared with benign thyroid disorders.

Indexed as

differentiated thyroid cancerinflammatory markerspapillary thyroid cancerplatelet indices

Identifiers

PMID34829306
PMCPMC8624142
OpenAlexW3209979683

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.